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Debt - Narrative (Details)
 1 Months Ended 3 Months Ended 9 Months Ended
Jul. 01, 2020
USD ($)
May 05, 2017
USD ($)
Sep. 30, 2019
USD ($)
D
May 31, 2017
USD ($)
Aug. 31, 2015
USD ($)
$ / shares
Sep. 30, 2019
USD ($)
Sep. 30, 2020
USD ($)
$ / shares
Sep. 30, 2019
USD ($)
Dec. 31, 2019
USD ($)
Long-term debt                  
Long-term debt             $ 302,971,000   $ 293,859,000
Current portion of long-term debt             0   20,000,000
Debt instrument additional amount available for repurchase             $ 37,500,000    
Conversion price per share (in dollars per share) | $ / shares             $ 6.00    
Adjustments to additional paid in capital, equity component of convertible debt           $ 119,489,000   $ 119,489,000  
Convertible debt | 3.00% Convertible senior notes due 2022                  
Long-term debt                  
Net carrying amount             $ 129,220,000   121,985,000
Debt principal amount         $ 150,000,000.0   $ 150,000,000   150,000,000
Interest rate ( as a percent )         3.00%        
Net proceeds from issuance of convertible notes         $ 145,400,000        
Trading days, number | D     20            
Stock price trigger     130.00%            
Business days, period     5 days            
Consecutive trading-day period     5 days            
Maximum product of the closing sale price of shares of the Company's common stock and the applicable conversion rate for such trading day             98.00%    
Conversion ratio         17.7487        
Conversion price per share (in dollars per share) | $ / shares         $ 56.34        
Convertible instruments principal and unpaid interest payable upon events of default     100.00%            
Minimum percentage of principal held by convertible debt instrument holders required to issue notice for declaration of principal and unpaid interest payable upon events of default     25.00%            
Term of the convertible notes     7 years   7 years        
Adjustments to additional paid in capital, equity component of convertible debt         $ 57,500,000        
Net deferred tax liability in connection with convertible notes         $ 22,300,000        
Fair value of convertible notes             $ 171,300,000   171,200,000
Remaining contractual life of the convertible notes             1 year 10 months 24 days    
Convertible debt | 3.00% Convertible senior notes due 2022 | Redemption on or after August 20, 2018                  
Long-term debt                  
Trading days, number | D     19            
Consecutive trading days, period | D     30            
Stock price trigger     130.00%            
Redemption price     100.00%            
Sinking fund             $ 0    
Convertible debt | 1.50% Convertible senior notes due 2026                  
Long-term debt                  
Net carrying amount             173,745,000   163,583,000
Debt principal amount             $ 287,500,000   $ 287,500,000
Interest rate ( as a percent )             1.50%   1.50%
Net proceeds from issuance of convertible notes             $ 279,300,000    
Conversion ratio     19.0404            
Conversion price per share (in dollars per share) | $ / shares             $ 52.52    
Term of the convertible notes             6 years    
Adjustments to additional paid in capital, equity component of convertible debt     $ 123,000,000.0            
Net deferred tax liability in connection with convertible notes             $ 25,300,000    
Fair value of convertible notes             $ 329,200,000   $ 335,000,000.0
MidCap Financial Trust                  
Long-term debt                  
Line of credit facility, maximum borrowing capacity       $ 60,000,000.0          
Proceeds from lines of credit   $ 40,000,000.0              
Line of credit facility, additional capacity available, net product revenue threshold       20,000,000.0          
Debt issuance costs       $ 400,000          
Debt instrument, floor interest rate       1.00%          
Debt instrument, basis spread on variable rate       6.15%          
Debt instrument, interest payment period       24 months          
Repayments of line of credit $ 18,300,000                
Payment of accrued interest 100,000                
Aggregate repayment of line of credit and accrued interest 18,400,000                
Termination and exit fees $ 600,000