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Fair value of financial instruments and investments - Marketable Securities, Balance Sheet Disclosures (Details) - USD ($) $ in Thousands | Dec. 31, 2020 | Dec. 31, 2019
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Debt Securities, Available-for-sale [Line Items] |  |
Total Marketable securities, Less Than 12 Months | $ 588,863 | $ 342,418
Total Marketable securities, More Than 12 Months | 305,975 | 56,117
Commercial paper |  |
Debt Securities, Available-for-sale [Line Items] |  |
Total Marketable securities, Less Than 12 Months | 276,837 | 158,098
Total Marketable securities, More Than 12 Months | 0 | 0
Corporate debt securities |  |
Debt Securities, Available-for-sale [Line Items] |  |
Total Marketable securities, Less Than 12 Months | 240,139 | 139,596
Total Marketable securities, More Than 12 Months | 235,520 | 49,738
Asset-backed securities |  |
Debt Securities, Available-for-sale [Line Items] |  |
Total Marketable securities, Less Than 12 Months | 6,363 | 44,724
Total Marketable securities, More Than 12 Months | 22,525 | $ 6,379
Government obligations |  |
Debt Securities, Available-for-sale [Line Items] |  |
Total Marketable securities, Less Than 12 Months | 65,524 |
Total Marketable securities, More Than 12 Months | $ 47,930 |

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- Definition Fair value of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 320 -Section 50 -Paragraph 3A -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=120252992&loc=SL120269850-112803 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 50 -Paragraph 3 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=121645371&loc=d3e27198-111563 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=121645371&loc=d3e27161-111563 + Details
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