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Selected quarterly financial data (Tables)

12 Months Ended

Dec. 31, 2020

Quarterly Financial Information Disclosure [Abstract]

Summary of quarterly data

The following financial information reflects all normal recurring adjustments, which are, in the opinion of management, necessary for a fair statement of the results of the interim periods. Summarized quarterly data for 2020 and 2019 are as follows:


		For the quarters ending (1)
		March 31			June 30			September 30			December 31
2020:
Net product revenue		$	68,196		$	75,239		$	82,708		$	107,258
Collaboration revenue			63			—			35,000			7,516
Royalty revenue			—			—			696			4,090
Operating expenses			161,250			262,512			173,535			215,238
Loss income from operations			(92,991)			(187,273)			(55,131)			(96,374)
Net loss			(112,687)			(181,427)			(69,692)			(74,354)
Basic and diluted net loss per common share		$	(1.81)		$	(2.78)		$	(1.03)		$	(1.08)
2019:
Net product revenue		$	53,054		$	85,476		$	71,369		$	81,407
Collaboration revenue			529			46			47			15,052
Operating expenses			122,723			124,280			131,891			169,243
Loss from operations			(69,140)			(38,758)			(60,475)			(72,784)
Net loss			(72,113)			(41,789)			(59,997)			(77,677)
Basic and diluted net loss per common share		$	(1.29)		$	(0.75)		$	(1.06)		$	(1.37)

(1)	The amounts were computed independently for each quarter and the sum of the quarters may not total the annual amounts.