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Acquisitions - Censa Acquisition (Details) - USD ($) $ in Thousands		12 Months Ended
	May 29, 2020	Dec. 31, 2020	Dec. 31, 2018
Acquisitions
Issuance of common stock related to acquisition		$ 42,869	$ 155,860
Censa
Acquisitions
Payments for asset acquisitions	$ 15,000
Payments for asset acquisitions, upfront payment	10,400
Payments for asset acquisitions, net assets	$ 4,600
Issuance of common stock related to acquisition (in shares)	845,364
Issuance of common stock related to acquisition	$ 42,900
Acquisition costs	700
Total consideration	58,600
Fair value of net assets acquired	4,600
Asset acquisition, cash and cash equivalents	3,800
Asset acquisition, other current assets	800
Asset acquisition, in-process research and development	54,000
Asset acquisition, development and regulatory milestones	109,000
Asset acquisition, initial milestone	30,000
Censa | Maximum
Acquisitions
Asset acquisition, milestone, amount	217,500
Asset acquisition, net sales milestone	$ 160,000
Censa | Research and development
Acquisitions
Asset acquisition, research and development expense		53,300
Censa | Selling, general and administrative
Acquisitions
Acquisition costs		$ 700

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