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Debt - Narrative (Details)				1 Months Ended			12 Months Ended
	Jul. 01, 2020 USD ($)	May 05, 2017 USD ($)	Aug. 31, 2015 USD ($) $ / shares	Sep. 30, 2019 USD ($) D	May 31, 2017 USD ($)	Aug. 31, 2015 USD ($) D $ / shares	Dec. 31, 2020 USD ($) $ / shares	Dec. 31, 2019 USD ($)
Long-term debt
Long-term debt							$ 309,145,000	$ 293,859,000
Current portion of long-term debt								20,000,000
Equity component of convertible notes, net								119,482,000
Additional Paid in Capital							2,171,746,000	1,795,351,000
Convertible debt | 1.50% Convertible senior notes due 2026
Long-term debt
Net carrying amount							177,377,000	163,583,000
Debt principal amount				$ 287,500,000			$ 287,500,000	287,500,000
Debt instrument additional amount available for repurchase				$ 37,500,000
Interest rate ( as a percent )				1.50%
Net proceeds from issuance of convertible notes				$ 279,300,000
Trading days, number | D				20
Stock price trigger				130.00%
Business days, period				5 days
Consecutive trading-day period				5 days
Maximum product of the closing sale price of shares of the Company's common stock and the applicable conversion rate for such trading day				98.00%
Conversion ratio				19.0404
Conversion price per share (in dollars per share) | $ / shares							$ 52.52
Sinking fund							$ 0
Convertible instruments principal and unpaid interest payable upon events of default				100.00%
Minimum percentage of principal held by convertible debt instrument holders required to issue notice for declaration of principal and unpaid interest payable upon events of default				25.00%
Term of the convertible notes				7 years			5 years 8 months 12 days
Equity component of convertible notes, net				$ 123,000,000.0
Net deferred tax liability in connection with convertible notes							$ 25,300,000
Convertible debt | 1.50% Convertible senior notes due 2026 | Redemption on or after September 20, 2023
Long-term debt
Trading days, number | D				19
Stock price trigger				130.00%
Redemption price as percent of principal amount				100.00%
Convertible debt | 3.00% Convertible senior notes due 2022
Long-term debt
Net carrying amount							131,763,000	121,985,000
Debt principal amount			$ 150,000,000.0			$ 150,000,000.0	150,000,000	150,000,000
Interest rate ( as a percent )			3.00%			3.00%
Net proceeds from issuance of convertible notes						$ 145,400,000
Trading days, number | D						20
Consecutive trading days, period | D						30
Stock price trigger						130.00%
Business days, period						5 days
Consecutive trading-day period						5 days
Maximum product of the closing sale price of shares of the Company's common stock and the applicable conversion rate for such trading day			98.00%			98.00%
Conversion ratio						17.7487
Conversion price per share (in dollars per share) | $ / shares			$ 56.34			$ 56.34
Convertible instruments principal and unpaid interest payable upon events of default						100.00%
Minimum percentage of principal held by convertible debt instrument holders required to issue notice for declaration of principal and unpaid interest payable upon events of default						25.00%
Term of the convertible notes			7 years			7 years
Net deferred tax liability in connection with convertible notes			$ 22,300,000			$ 22,300,000
Additional Paid in Capital							$ 57,500,000
Remaining contractual life of the convertible notes							1 year 7 months 6 days
Convertible debt | 3.00% Convertible senior notes due 2022 | Redemption on or after September 20, 2023
Long-term debt
Consecutive trading days, period | D				30
Convertible debt | 3.00% Convertible senior notes due 2022 | Redemption on or after August 20, 2018
Long-term debt
Trading days, number | D						19
Consecutive trading days, period | D						30
Stock price trigger						130.00%
Redemption price as percent of principal amount						100.00%
Sinking fund							$ 0
Convertible debt instruments redeemed							0
MidCap Financial Trust
Long-term debt
Line of credit facility, maximum borrowing capacity					$ 60,000,000.0
Proceeds from lines of credit		$ 40,000,000.0
Debt issuance costs					$ 400,000
Repayments of debt								11,700,000
Net carrying amount								28,300,000
Long-term debt								$ 20,000,000.0
Current portion of long-term debt							$ 8,300,000
Debt instrument, interest payment period					24 months
Repayments of line of credit	$ 18,300,000
Payment of accrued interest	100,000
Aggregate repayment of line of credit and accrued interest	18,400,000
Termination and exit fees	$ 600,000
MidCap Financial Trust | LIBOR
Long-term debt
Debt instrument, floor interest rate					1.00%
Debt instrument, basis spread on variable rate					6.15%

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- Definition

Amount of convertible debt instruments redeemed.

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Debt Instrument Additional Amount Available For Repurchase

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Threshold period of specified business days within which the maximum product of the closing sale price of shares of the entity's common stock and the applicable conversion rate for such trading day triggers the conversion feature.

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Threshold period of specified consecutive trading days within which the maximum product of the closing sale price of shares of the entity's common stock and the applicable conversion rate for such trading day triggers the conversion feature.

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Debt Instrument, Floor Interest Rate

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Amount of net deferred tax liability attributable to taxable temporary differences from issuance of convertible debt instruments.

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Excess of issue price over par or stated value of the entity's capital stock and amounts received from other transactions involving the entity's stock or stockholders. Includes adjustments to additional paid in capital. Some examples of such adjustments include recording the issuance of debt with a beneficial conversion feature and certain tax consequences of equity instruments awarded to employees. Use this element for the aggregate amount of additional paid-in capital associated with common and preferred stock. For additional paid-in capital associated with only common stock, use the element additional paid in capital, common stock. For additional paid-in capital associated with only preferred stock, use the element additional paid in capital, preferred stock.

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Adjustment to additional paid in capital resulting from the recognition of convertible debt instruments as two separate components - a debt component and an equity component. This bifurcation may result in a basis difference associated with the liability component that represents a temporary difference for purposes of applying accounting for income taxes. The initial recognition of deferred taxes for the tax effect of that temporary difference is as an adjustment to additional paid in capital.

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Percentage points added to the reference rate to compute the variable rate on the debt instrument.

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Cumulative amount paid into a fund, which is used to retire the debt instrument.

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Contractual interest rate for funds borrowed, under the debt agreement.

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Period of time between issuance and maturity of debt instrument, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Amount, before accumulated amortization, of debt issuance costs related to line of credit arrangements. Includes, but is not limited to, legal, accounting, underwriting, printing, and registration costs.

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Maximum borrowing capacity under the credit facility without consideration of any current restrictions on the amount that could be borrowed or the amounts currently outstanding under the facility.

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Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.

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Amount after unamortized (discount) premium and debt issuance costs of long-term debt classified as noncurrent and excluding amounts to be repaid within one year or the normal operating cycle, if longer. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 15
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-Section S99
-Paragraph 1
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-URI http://asc.fasb.org/extlink&oid=120395691&loc=d3e23780-122690

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