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Stock award plan - Narrative (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 3 Months Ended |
--- | --- | --- | ---
Dec. 31, 2020 | Jun. 30, 2016 | May 31, 2013 | Mar. 31, 2021 | Mar. 31, 2020 | Jan. 31, 2020
Stock option plan |  |  |  |  |  |
Share-based compensation expense |  |  |  | $ 25,707 | $ 15,220 |
Restricted stock |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Grants in period (in shares) |  |  |  | 850,365 |  |
Stock option |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Granted (in shares) |  |  |  | 1,954,690 |  |
Expected dividend yield (as a percent) |  |  |  | 0.00% |  |
Weighted average grant date fair value (in dollars per share) |  |  |  | $ 46.90 |  |
Risk-free interest rate (as a percent) |  |  |  | 0.51% |  |
Expected volatility (as a percent) |  |  |  | 88.61% |  |
Expected term (in years) |  |  |  | 5 years 6 months |  |
1998 Employee, Director, and Consultant Stock Option Plan, 2009 Equity and Long-term Incentive Plan, and 2013 Stock Incentive Plan | Common stock |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Number of shares available for issuance |  |  |  | 0 |  |
1998 Employee, Director, and Consultant Stock Option Plan, 2009 Equity and Long-term Incentive Plan, and 2013 Stock Incentive Plan | Common stock | Maximum |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Number of shares subject to outstanding awards (in shares) |  |  | 3,040,444 |  |  |
2009 Equity and Long Term Incentive Plan and 2013 Stock Incentive Plan | Common stock |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Number of shares available for issuance |  |  | 122,296 |  |  |
2013 Long Term Incentive Plan | Minimum |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Share based Compensation Arrangement by Share based Payment Award Number of Shares Authorized Annual Increase Number |  |  | 2,500,000 |  |  |
Annual increase in the number of shares outstanding on the first day of the fiscal year |  |  | 4.00% |  |  |
2013 Long Term Incentive Plan | Common stock |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Number of shares available for issuance |  |  |  | 826,484 |  |
2020 Inducement Stock Incentive Plan | Common stock |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Number of shares available for issuance |  |  |  | 1,205,375 |  |
Number of additional shares authorized (in shares) | 1,000,000 |  |  |  |  |
2020 Inducement Stock Incentive Plan | Common stock | Maximum |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Number of shares authorized (in shares) |  |  |  |  |  | 1,000,000
2020 Inducement Stock Incentive Plan | Stock option |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Inducement grants for non-statutory stock options (in shares) |  |  |  | 13,465 |  |
Employee Stock Purchase Plan |  |  |  |  |  |
Stock option plan |  |  |  |  |  |
Number of shares authorized (in shares) |  | 1,000,000 |  |  |  |
Share-based compensation expense |  |  |  | $ 500 |  |
Award requisite service period |  | 6 months |  |  |  |
Purchase price of common stock, percent |  | 85.00% |  |  |  |
Employee stock purchase plan, voting percentage limit |  | 5.00% |  |  |  |

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- Definition Represents the number of shares to be added annually on the first day of each fiscal year in the number of shares authorized. + References No definition available. + Details
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- Definition Amount of expense for award under share-based payment arrangement. Excludes amount capitalized. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5047-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1)(i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2)(iii)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(iii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(ii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The risk-free interest rate assumption that is used in valuing an option on its own shares. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(iv) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.D.2) -URI http://asc.fasb.org/extlink&oid=115993241&loc=d3e301413-122809 + Details
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