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v3.21.1

Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands | Common stock | Additional paid-in capital Cumulative Effect Adjustment | Additional paid-in capital | Accumulated other comprehensive income (loss) | Accumulated deficit Cumulative Effect Adjustment | Accumulated deficit | Cumulative Effect Adjustment | Total
--- | --- | --- | --- | --- | --- | --- | --- | ---
Balance (in shares) at Dec. 31, 2019 | 61,935,870 |  |  |  |  |  |  |
Balance at the beginning of the period at Dec. 31, 2019 | $ 62 |  | $ 1,795,351 | $ (10,584) |  | $ (1,190,499) |  | $ 594,330
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issuance of common stock related to equity offerings (in shares) | 262,205 |  |  |  |  |  |  |
Issuance of common stock related to equity offering |  |  | 13,503 |  |  |  |  | 13,503
Exercise of options (in shares) | 379,684 |  |  |  |  |  |  |
Exercise of options |  |  | 9,987 |  |  |  |  | 9,987
Restricted stock vesting and issuance (in shares) | 180,761 |  |  |  |  |  |  |
Share-based compensation expense |  |  | 15,220 |  |  |  |  | 15,220
Other |  |  |  |  |  | (218) |  | (218)
Net loss |  |  |  |  |  | (112,687) |  | (112,687)
Comprehensive income |  |  |  | 8,599 |  |  |  | 8,599
Balance (in shares) at Mar. 31, 2020 | 62,758,520 |  |  |  |  |  |  |
Balance at the end of the period at Mar. 31, 2020 | $ 62 |  | 1,834,061 | (1,985) |  | (1,303,404) |  | 528,734
Balance (in shares) at Dec. 31, 2020 | 69,718,096 |  |  |  |  |  |  |
Balance at the beginning of the period at Dec. 31, 2020 | $ 70 | $ (175,236) | 2,171,746 | (60,957) | $ 54,796 | (1,628,877) | $ (120,440) | 481,982
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Exercise of options (in shares) | 415,783 |  |  |  |  |  |  |
Exercise of options |  |  | 11,755 |  |  |  |  | 11,755
Restricted stock vesting and issuance (in shares) | 272,026 |  |  |  |  |  |  |
Share-based compensation expense |  |  | 25,707 |  |  |  |  | 25,707
Net loss |  |  |  |  |  | (128,642) |  | (128,642)
Comprehensive income |  |  |  | 22,214 |  |  |  | 22,214
Balance (in shares) at Mar. 31, 2021 | 70,405,905 |  |  |  |  |  |  |
Balance at the end of the period at Mar. 31, 2021 | $ 70 |  | $ 2,033,972 | $ (38,743) |  | $ (1,702,723) |  | $ 292,576

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