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Summary of significant accounting policies - Narrative (Details)
$ in Thousands
 3 Months Ended 6 Months Ended
Jul. 17, 2020
USD ($)
Dec. 22, 2017
Jun. 30, 2021
USD ($)
Jun. 30, 2020
USD ($)
Jun. 30, 2021
USD ($)
segment
Jun. 30, 2020
USD ($)
Dec. 31, 2020
USD ($)
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Letters of Credit     $ 7,500   $ 7,500    
Term for letter of credit (in years)         5 years    
Number of operating segments | segment         1    
Allowance for credit loss     0   $ 0    
Increase in allowance for credit losses     0 $ 0 0 $ 0  
Allowance for doubtful accounts receivable     100   100   $ 100
Deferred payroll taxes provided for under CARES Act         2,500    
Cash consideration received from Royalty Purchase Agreement $ 650,000            
Federal income tax statutory rate   21.00%          
Deferred tax liability     122,000   $ 122,000    
Minimum              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Term for letter of credit (in years)         5 years    
Fifth Anniversary              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Letters of Credit     3,800   $ 3,800    
Non-US              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Net product revenue     54,000 39,000 101,700 79,800  
United States              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Net product revenue     $ 49,100 $ 36,200 $ 92,700 $ 63,600