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Summary of significant accounting policies - Collaboration and Royalty Revenue (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended		6 Months Ended
	Mar. 31, 2021	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020
Collaboration and royalty revenue
Revenue		$ 116,676	$ 75,239	$ 234,620	$ 143,498
Collaboration revenue
Collaboration and royalty revenue
Revenue		0	0	20,007	63
Royalty revenue
Collaboration and royalty revenue
Revenue		13,563	0	20,220
SMA License Agreement | Collaboration revenue
Collaboration and royalty revenue
Revenue		0	0	20,000	100
SMA License Agreement | Royalty revenue
Collaboration and royalty revenue
Revenue		13,600	$ 0	20,200	0
SMA License Agreement | Sales Milestones
Collaboration and royalty revenue
Milestone payments received	$ 20,000	$ 0		$ 20,000	$ 0

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