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Debt - (Tables) | 9 Months Ended
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Sep. 30, 2021
Debt Instrument, Redemption [Line Items] |
Summary of liability for sale of future royalties | ​
​ | ​ | ​ | ​ | ​
​ |  | Nine Months Ended September 30, | ​
Liability for sale of future royalties- (current and noncurrent) | ​ | 2021 | ​
Beginning balance as of December 31, 2020 | ​ | $ | 679,762 | ​
Less: Non-cash royalty revenue payable to RPI | ​ | ​ | (14,317) | ​
Plus: Non-cash interest expense recognized | ​ | ​ | 57,755 | ​
Ending balance | ​ | $ | 723,200 | ​
Effective interest rate as of September 30, 2021 | ​ |  | 11 | %
1.50% Convertible senior notes due 2026 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
Liability component |  | September 30, 2021 | ​ | December 31, 2020
Principal | ​ | $ | 287,500 | ​ | $ | 287,500
Less: Debt issuance costs | ​ |  | (5,896) | ​ |  | (4,058)
Less: Debt discount, net(1) | ​ |  | — | ​ |  | (106,065)
Net carrying amount | ​ | $ | 281,604 | ​ | $ | 177,377
Summary of interest expense recognized related to the Convertible Notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended September 30, | ​ | ​ | Nine Months Ended September 30, | ​ | ​ | ​
​ |  | 2021 |  | ​ | 2020 | ​ | ​ | 2021 |  | ​ | 2020 | ​ | ​ | ​
Contractual interest expense | ​ | $ | 1,081 | ​ | $ | 1,081 | ​ | ​ | $ | 3,217 | ​ | $ | 3,223 | ​ | ​ | ​
Amortization of debt issuance costs | ​ |  | 283 | ​ | ​ | 127 | ​ | ​ |  | 839 | ​ |  | 374 | ​ | ​ | ​
Amortization of debt discount | ​ | ​ | — | ​ | ​ | 3,313 | ​ | ​ | ​ | — | ​ | ​ | 9,786 | ​ | ​ | ​
Total | ​ | $ | 1,364 | ​ | $ | 4,521 | ​ | ​ | $ | 4,056 | ​ | $ | 13,383 | ​ | ​ | ​
Effective interest rate of the liability component | ​ |  | 1.9 | % | ​ | 10.2 | % | ​ |  | 1.9 | % | ​ | 10.2 | % | ​ | ​
3.00% Convertible senior notes due 2022 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
Liability component |  | September 30, 2021 |  | December 31, 2020
Principal | ​ | $ | 150,000 | ​ | $ | 150,000
Less: Debt issuance costs | ​ |  | (642) | ​ |  | (865)
Less: Debt discount, net (1) | ​ |  | — | ​ |  | (17,372)
Net carrying amount | ​ | $ | 149,358 | ​ | $ | 131,763
Summary of interest expense recognized related to the Convertible Notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​ | ​ | ​ |  | ​
​ | ​ | Three Months Ended September 30, |  | Nine Months Ended September 30, |  | ​
​ |  | 2021 |  | 2020 |  | 2021 |  | 2020 |  | ​
Contractual interest expense | ​ | $ | 1,134 | ​ | $ | 1,131 | ​ | $ | 3,375 | ​ | $ | 3,375 | ​ | ​
Amortization of debt issuance costs | ​ |  | 182 | ​ |  | 118 | ​ |  | 538 | ​ |  | 343 | ​ | ​
Amortization of debt discount | ​ |  | — | ​ |  | 2,372 | ​ |  | — | ​ |  | 6,892 | ​ | ​
Total | ​ | $ | 1,316 | ​ | $ | 3,621 | ​ | $ | 3,913 | ​ | $ | 10,610 | ​ | ​
Effective interest rate of the liability component | ​ |  | 3.5 | % |  | 11.0 | % |  | 3.5 | % |  | 11.0 | % | ​

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- Definition Tabular disclosure of borrowings which can be exchanged for a specified number of another security at the option of the issuer or the holder. Disclosures include, but are not limited to, principal amount, amortized premium or discount, and amount of liability and equity components. + References No definition available. + Details
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