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Summary of significant accounting policies - Narrative (Details)
$ in Thousands
 3 Months Ended 9 Months Ended
Jul. 17, 2020
USD ($)
Dec. 22, 2017
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2021
USD ($)
segment
Sep. 30, 2020
USD ($)
Dec. 31, 2020
USD ($)
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Letters of Credit     $ 7,500   $ 7,500    
Term for letter of credit (in years)         5 years    
Number of operating segments | segment         1    
Allowance for credit loss     0   $ 0    
Increase in allowance for credit losses     0 $ 0      
Allowance for doubtful accounts receivable     300   300   $ 100
Revenue     138,743 118,404 373,364 $ 261,902  
Deferred payroll taxes provided for under CARES Act         2,500    
Cash consideration received from Royalty Purchase Agreement $ 650,000         650,000  
Federal income tax statutory rate   21.00%          
Deferred tax liability     122,000   $ 122,000    
Minimum              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Term for letter of credit (in years)         5 years    
Fifth Anniversary              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Letters of Credit     3,800   $ 3,800    
Net product revenue              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Revenue     115,605 82,708 309,998 226,143  
Net product revenue | Non-US              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Revenue     68,500 44,200 170,200 124,000  
Emflaza | United States              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Revenue     47,100 38,500 139,800 102,100  
Translarna | Non-US              
New Accounting Pronouncements or Change in Accounting Principle [Line Items]              
Revenue     $ 67,200 $ 43,400 $ 166,300 $ 122,700