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Fixed assets | 12 Months Ended
--- | ---
Dec. 31, 2021
Property, Plant and Equipment [Abstract] |
Fixed assets | 5. Fixed assets Fixed assets, net were as follows at December 31, 2021 and 2020: ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | December 31,
​ |  | 2021 |  | 2020
Leasehold improvements | ​ | $ | 19,937 | ​ | $ | 8,072
Computer equipment and software | ​ |  | 13,812 | ​ |  | 11,471
Machinery and lab equipment | ​ | ​ | 33,187 | ​ | ​ | 23,430
Furniture and fixtures | ​ |  | 3,805 | ​ |  | 3,844
Assets in process | ​ |  | 9,017 | ​ |  | 5,076
​ | ​ |  | 79,758 | ​ |  | 51,893
Less accumulated depreciation | ​ |  | (27,173) | ​ |  | (18,062)
Total | ​ | $ | 52,585 | ​ | $ | 33,831
​ Depreciation expense was approximately $9.4 million, $6.6 million, and $4.7 million for the years ended December 31, 2021, 2020, and 2019, respectively.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 6 -URI http://asc.fasb.org/extlink&oid=120429125&loc=d3e99893-112916 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -URI http://asc.fasb.org/topic&trid=2155823 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 7 -URI http://asc.fasb.org/extlink&oid=120429125&loc=SL120174063-112916 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 958 -SubTopic 360 -Section 50 -Paragraph 1 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=120429125&loc=d3e99779-112916 + Details
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