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Leases | 12 Months Ended
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Dec. 31, 2021
Leases |
Leases | 6. Leases The Company leases office space in South Plainfield, New Jersey for its principal office under three noncancelable operating leases through May 2022 and August 2024, in addition to office and laboratory space in Bridgewater, New Jersey and office space in various countries for international employees primarily through workspace providers. The Company also leases approximately 220,500 square feet of office, manufacturing and laboratory space at a facility located in Hopewell Township, New Jersey (the “Campus”) pursuant to a Lease Agreement (the “Lease”) with Hopewell Campus Owner LLC (the “Landlord”). The rental term of the Lease commenced on July 1, 2020 and has an initial term of fifteen years (the “Initial Term”), with two consecutive ten year renewal periods, each at the Company’s option. The aggregate rent for the Initial Term will be approximately $111.5 million. The rental rate for the renewal periods will be 95% of the Prevailing Market Rate (as defined in the Lease) and determined at the time of the exercise of the renewal. The Company is also responsible for maintaining certain insurance and the payment of proportional taxes, utilities and common area operating expenses. The Lease contains customary events of default, representations, warranties and covenants. Subject to the terms of the Lease, the Company has a right of first refusal to rent certain other space of the Campus, which would be triggered upon the Landlord’s issuance of a second round proposal or letter of intent to another tenant for such space. The Company also may seek to build a new separate building on the Campus, which may not contain less than 75,000 square feet (the “New Building”). Upon receipt of notice of the Company’s intention to build the New Building, the Landlord may, in its sole discretion, construct and lease the New Building to the Company or enter into a ground lease with the Company permitting the Company to construct the New Building. Rent terms for the New Building would be determined based on the land value, construction and project costs subject to whether the Landlord or Company constructs the New Building. On June 19, 2020, the Company entered into a commercial manufacturing service agreement for a term of 12.5 years with MassBiologics of the University of Massachusetts Medical School ("MassBio"). The agreement will expire on December 31, 2032 unless the Company terminates it on 24 months prior written notice to MassBio. Pursuant to the terms of the agreement, MassBio agreed to provide the Company with four dedicated rooms for its gene therapy AADC program. The Company concluded that the agreement contains an embedded lease as the Company controls the use of the four dedicated rooms and the equipment therein. The agreement included guaranteed lease payments of $15.0 million at the onset of the agreement and $3.0 million annually thereafter. The present value of the guaranteed lease payments was determined to be $41.4 million, which exceeded the assessed fair value of the Company’s share of the building. Therefore, the Company determined that the agreement was a finance lease, for which the Company recorded a finance lease ROU asset and corresponding finance lease liability at the onset of the lease agreement. Given that the leased asset is designed for the production of PTC’s AADC program and would not have an alternate use outside the PTC gene therapy platform without incurring significant costs, the Company determined that the lease should be treated as research and development expense under ASC 730. Accordingly, the full $41.4 million relating to the finance lease ROU asset was written off and expensed to research and development during the year ended December 31, 2020. The remaining balance for the finance lease ROU asset related to this arrangement is $0 as of December 31, 2021 and as of December 31, 2020. As of December 31, 2021, the balance of the finance lease liabilities-current and finance lease liabilities-non-current are $3.0 million and $20.1 million, respectively, and are directly related to the Company’s MassBio agreement. As of December 31, 2020, the balance of the finance lease liabilities-current and finance lease liabilities non-current were $1.3 million and $23.1 million, respectively. Additionally, during the years ended December 30, 2021 and December 30, 2020, the Company recorded finance lease costs of $1.7 million and $0.9 million, respectively, related to interest on the lease liability. The Company also leases certain vehicles, lab equipment, and office equipment under operating leases. The Company’s operating leases have remaining lease terms ranging from 0.1 years to 13.5 years and certain leases include renewal options to extend the lease for up to 10 years. Rent expense was approximately $21.4 million, $15.3 million, and $6.0 million for the years ended December 31, 2021, 2020 and 2019. The components of lease expense were as follows: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended December 31, 2021 | ​ | Year Ended December 31, 2020 | ​ | Year Ended December 31, 2019
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Operating Lease Cost | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​
Fixed lease cost | ​ | $ | 16,411 | ​ | $ | 12,368 | ​ | $ | 4,929
Variable lease cost | ​ | ​ | 4,361 | ​ | ​ | 2,448 | ​ | ​ | 694
Short-term lease cost | ​ | ​ | 656 | ​ | ​ | 450 | ​ | ​ | 350
Total operating lease cost | ​ | $ | 21,428 | ​ | $ | 15,266 | ​ | $ | 5,973
​ Total operating lease cost is a component of operating expenses on the consolidated statements of operations. The Company did not enter into any new material leases during the year ended December 31, 2021. The decrease in the operating lease ROU asset and operating lease liability during the year ended December 31, 2021 resulted from the termination of the Company’s office leases in Sweden and Washington DC. ​ Supplemental lease term and discount rate information related to leases was as follows: ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | December 31, 2021 |  | ​ | December 31, 2020 |
Weighted-average remaining lease terms - operating leases (years) |  | 10.87 | ​ | ​ | 11.49 | ​
Weighted-average discount rate - operating leases | ​ | 8.91 | % | ​ | 8.86 | %
Weighted-average remaining lease terms - finance lease (years) |  | 11.00 | ​ | ​ | 12.00 | ​
Weighted-average discount rate - finance lease |  | 7.80 | % | ​ | 7.80 | %
​ Supplemental cash flow information related to leases was as follows: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | Year Ended December 31,
​ | 2021 |  | 2020 | ​ | 2019
Cash paid for amounts included in the measurement of lease liabilities: | ​ |  | ​ | ​ |  | ​ | ​ | ​
Operating cash flows from operating leases | $ | 13,683 | ​ | $ | 8,462 | ​ | $ | 4,466
Financing cash flows from finance lease | ​ | 2,224 | ​ | ​ | 17,829 | ​ | ​ | —
Operating cash flows from finance leases | ​ | 776 | ​ | ​ | 171 | ​ | ​ | —
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Right-of-use assets obtained in exchange for lease obligations: |  | ​ | ​ |  |  | ​ | ​ | ​
Operating leases | $ | 645 | ​ | $ | 76,811 | ​ | $ | 17,389
Finance lease | ​ | — | ​ | ​ | 41,382 | ​ | ​ | —
​ Future minimum lease payments under non-cancelable leases as of December 31, 2021 were as follows: ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Operating Leases |  | Finance Lease
2022 | ​ | $ | 13,443 | ​ | $ | 3,000
2023 | ​ |  | 13,068 | ​ |  | 3,000
2024 | ​ |  | 12,343 | ​ |  | 3,000
2025 | ​ |  | 11,221 | ​ |  | 3,000
2026 and thereafter | ​ |  | 80,771 | ​ |  | 21,000
Total lease payments | ​ |  | 130,846 | ​ |  | 33,000
Less: Imputed Interest expense | ​ |  | 49,954 | ​ |  | 9,947
Total | ​ | $ | 80,892 | ​ | $ | 23,053
​ In conjunction with the BioElectron Asset Purchase Agreement by and between the Company and BioElectron, the Company acquired BioElectron’s lease in Mountain View, California. As substantially all of the fair value of the gross assets acquired was related to vatiquinone, the relative fair value allocated to the right of use asset and corresponding lease liability for the Mountain View lease was determined to be immaterial, and accordingly is not included in the tables above. The future minimum lease payments for the Mountainview lease are $1.4 million for 2022 and $0 thereafter.

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