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Leases - Narrative (Details) $ in Thousands |  | 12 Months Ended |
--- | --- | --- | ---
Jun. 19, 2020 USD ($) room | Dec. 31, 2021 USD ($) ft² lease | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($) | Jul. 01, 2020 USD ($) ft² item
Leases |  |  |  |  |
Number of operating leases | lease |  | 3 |  |  |
Operating lease, expense |  | $ 21,400 | $ 15,300 | $ 6,000 |
Finance lease liabilities- current |  | 3,000 | 1,276 |  |
Finance lease liabilities- noncurrent |  | 20,053 | 23,053 |  |
Aggregate rent, Initial term |  | 130,846 |  |  |
2022 |  | 13,443 |  |  |
Finance Lease, Right-of-Use Asset |  | 0 | 0 |  |
Research and development |  | 540,684 | 477,643 | $ 257,452 |
MassBio |  |  |  |  |
Leases |  |  |  |  |
Written notice required for early lease termination | 24 months |  |  |  |
Finance lease cost |  | $ 1,700 | 900 |  |
Number of dedicated rooms provided for gene therapy AADC program | room | 4 |  |  |  |
Guaranteed lease payment due at onset of the lease agreement | $ 15,000 |  |  |  |
Guaranteed lease payments due annually | 3,000 |  |  |  |
Present value of guaranteed lease payments | $ 41,400 |  |  |  |
Finance lease, term of contract | 12 years 6 months |  |  |  |
Research and development |  |  | $ 41,400 |  |
Minimum |  |  |  |  |
Leases |  |  |  |  |
Operating lease, term of contract |  | 1 month 6 days |  |  |
Maximum |  |  |  |  |
Leases |  |  |  |  |
Operating lease, term of contract |  | 13 years 6 months |  |  |
Renewal Term |  | 10 years |  |  |
New Building | Minimum |  |  |  |  |
Leases |  |  |  |  |
Area of real estate property | ft² |  | 75,000 |  |  |
Hopewell Campus |  |  |  |  |
Leases |  |  |  |  |
Operating lease, term of contract |  |  |  |  | 15 years
Area of real estate property | ft² |  |  |  |  | 220,500
Renewal Term |  |  |  |  | 10 years
Number of renewable terms | item |  |  |  |  | 2
Aggregate rent, Initial term |  |  |  |  | $ 111,500
Percent of market rate |  |  |  |  | 95.00%
Mountain View |  |  |  |  |
Leases |  |  |  |  |
2022 |  | $ 1,400 |  |  |
Thereafter |  | $ 0 |  |  |

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- Definition Amount of lessee's undiscounted obligation for lease payment for operating lease due after second fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). + References No definition available. + Details
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