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Fair value of financial instruments and investments - Marketable Securities, Balance Sheet Disclosures (Details) - USD ($) $ in Thousands | Dec. 31, 2021 | Dec. 31, 2020
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Debt Securities, Available-for-sale [Line Items] |  |
Marketable securities, Less Than 12 Months | $ 221,611 | $ 588,863
Marketable securities, More Than 12 Months | 155,074 | 305,975
Commercial paper |  |
Debt Securities, Available-for-sale [Line Items] |  |
Marketable securities, Less Than 12 Months | 75,279 | 276,837
Marketable securities, More Than 12 Months | 0 |
Corporate debt securities |  |
Debt Securities, Available-for-sale [Line Items] |  |
Marketable securities, Less Than 12 Months | 131,606 | 240,139
Marketable securities, More Than 12 Months | 136,077 | 235,520
Asset-backed securities |  |
Debt Securities, Available-for-sale [Line Items] |  |
Marketable securities, Less Than 12 Months | 8,724 | 6,363
Marketable securities, More Than 12 Months | 6,574 | 22,525
Government obligations |  |
Debt Securities, Available-for-sale [Line Items] |  |
Marketable securities, Less Than 12 Months | 6,002 | 65,524
Marketable securities, More Than 12 Months | $ 12,423 | $ 47,930

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- Definition Fair value of investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale), with single maturity date and allocated without single maturity date, maturing in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 320 -Section 50 -Paragraph 3A -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123599081&loc=SL120269850-112803 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 50 -Paragraph 3 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123581744&loc=d3e27198-111563 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 320 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=123581744&loc=d3e27161-111563 + Details
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