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Cover - USD ($)
 12 Months Ended
Dec. 31, 2021
Feb. 18, 2022
Jun. 30, 2021
Cover [Abstract]      
Document Type 10-K    
Document Annual Report true    
Document Period End Date Dec. 31, 2021    
Document Transition Report false    
Entity File Number 001-35969    
Entity Registrant Name PTC THERAPEUTICS, INC.    
Entity Incorporation, State or Country Code DE    
Entity Tax Identification Number 04-3416587    
Entity Address, Address Line One 100 Corporate Court    
Entity Address, City or Town South Plainfield,    
Entity Address, State or Province NJ    
Entity Address, Postal Zip Code 07080    
City Area Code 908    
Local Phone Number 222-7000    
Title of 12(b) Security Common Stock, $0.001 par value per share    
Trading Symbol PTCT    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer Yes    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Large Accelerated Filer    
Entity Small Business false    
Entity Emerging Growth Company false    
ICFR Auditor Attestation Flag true    
Entity Shell Company false    
Entity Public Float     $ 2,191,128,010
Entity Common Stock, Shares Outstanding   71,362,471  
Documents Incorporated By Reference

DOCUMENTS INCORPORATED BY REFERENCE

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Part III of this Annual Report incorporates by reference information from the definitive Proxy Statement for the registrant’s 2022 Annual Meeting of Shareholders which is expected to be filed with the Securities and Exchange Commission not later than 120 days after the registrant’s fiscal year ended December 31, 2021.

    
Entity Central Index Key 0001070081    
Current Fiscal Year End Date --12-31    
Document Fiscal Year Focus 2021    
Document Fiscal Period Focus FY    
Amendment Flag false    
Auditor Name Ernst & Young LLP    
Auditor Firm ID 42    
Auditor Location Iselin, New Jersey