The amount of guaranteed lease payments due annually under the lease agreement.

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The amount of guaranteed lease payments due at the onset of the lease agreement.

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The present value of guaranteed lease payments under the lease agreement.

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Amount of lessee's undiscounted obligation for lease payment for operating lease due after second fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

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Required period of written notification to lessor prior to early termination required by terms of the lease agreement.

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- Definition

The number of dedicated rooms provided for gene therapy AADC program under terms of the agreement.

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Number Of Operating Leases

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Number of renewable terms.

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Percent Of Market Rate

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- Definition

Area of a real estate property.

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- Definition

Amount of interest expense on finance lease liability.

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Present value of lessee's discounted obligation for lease payments from finance lease, classified as current.

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Present value of lessee's discounted obligation for lease payments from finance lease, classified as noncurrent.

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Amount, after accumulated amortization, of right-of-use asset from finance lease.

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Term of lessee's finance lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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No definition available.

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Amount of lessee's undiscounted obligation for lease payment for operating lease.

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Amount of lessee's undiscounted obligation for lease payment for operating lease to be paid in next fiscal year following current fiscal year. Excludes interim and annual periods when interim periods are reported from current statement of financial position date (rolling approach).

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Term of lessee's operating lease renewal, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Term of lessee's operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Amount of operating lease expense. Excludes sublease income.

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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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Leases - Narrative (Details) $ in Thousands		12 Months Ended
Leases - Narrative (Details) $ in Thousands	Jun. 19, 2020 USD ($) room	Dec. 31, 2021 USD ($) ft² lease	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Jul. 01, 2020 USD ($) ft² item
Leases
Number of operating leases \| lease		3
Operating lease, expense		$ 21,400	$ 15,300	$ 6,000
Finance lease liabilities- current		3,000	1,276
Finance lease liabilities- noncurrent		20,053	23,053
Aggregate rent, Initial term		130,846
2022		13,443
Finance Lease, Right-of-Use Asset		0	0
Research and development		540,684	477,643	$ 257,452
MassBio
Leases
Written notice required for early lease termination	24 months
Finance lease cost		$ 1,700	900
Number of dedicated rooms provided for gene therapy AADC program \| room	4
Guaranteed lease payment due at onset of the lease agreement	$ 15,000
Guaranteed lease payments due annually	3,000
Present value of guaranteed lease payments	$ 41,400
Finance lease, term of contract	12 years 6 months
Research and development			$ 41,400
Minimum
Leases
Operating lease, term of contract		1 month 6 days
Maximum
Leases
Operating lease, term of contract		13 years 6 months
Renewal Term		10 years
New Building \| Minimum
Leases
Area of real estate property \| ft²		75,000
Hopewell Campus
Leases
Operating lease, term of contract					15 years
Area of real estate property \| ft²					220,500
Renewal Term					10 years
Number of renewable terms \| item					2
Aggregate rent, Initial term					$ 111,500
Percent of market rate					95.00%
Mountain View
Leases
2022		$ 1,400
Thereafter		$ 0