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v3.22.1

Debt - (Tables) | 3 Months Ended
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Mar. 31, 2022
Debt Instrument, Redemption [Line Items] |
Summary of liability for sale of future royalties | ​
​ | ​ | ​ | ​ | ​
​ |  | Three Months Ended March 31, | ​
Liability for sale of future royalties- (current and noncurrent) | ​ | 2022 | ​
Beginning balance as of December 31, 2021 | ​ | $ | 733,985 | ​
Less: Non-cash royalty revenue payable to RPI | ​ | ​ | (8,113) | ​
Plus: Non-cash interest expense recognized | ​ | ​ | 18,874 | ​
Ending balance | ​ | $ | 744,746 | ​
Effective interest rate as of March 31, 2022 | ​ |  | 10.1 | %
1.50% Convertible senior notes due 2026 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ | ​ | ​ | ​ | ​ | ​
Liability component | ​ | March 31, 2022 | ​ | December 31, 2021 | ​
Principal | ​ | $ | 287,500 | ​ | $ | 287,500 | ​
Less: Debt issuance costs | ​ |  | (5,324) | ​ |  | (5,606) | ​
Net carrying amount | ​ | $ | 282,176 | ​ | $ | 281,894 | ​
Summary of interest expense recognized related to the Convertible Notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ | ​ | ​ | ​ | ​ |
​ | ​ | Three Months Ended March 31,
​ | ​ | 2022 |  | ​ | 2021 | ​
Contractual interest expense | ​ | $ | 1,069 | ​ | $ | 1,069 | ​
Amortization of debt issuance costs | ​ | ​ | 283 | ​ | ​ | 277 | ​
Total | ​ | $ | 1,352 | ​ | $ | 1,346 | ​
Effective interest rate of the liability component | ​ | ​ | 1.9 | % | ​ | 1.9 | %
3.00% Convertible senior notes due 2022 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Liability component |  | March 31, 2022 |  | December 31, 2021 | ​
Principal | ​ | $ | 150,000 | ​ | $ | 150,000 | ​
Less: Debt issuance costs | ​ |  | (279) | ​ |  | (460) | ​
Net carrying amount | ​ | $ | 149,721 | ​ | $ | 149,540 | ​
Summary of interest expense recognized related to the Convertible Notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ |  | ​
​ | Three Months Ended March 31, |  | ​
​ | 2022 |  | 2021 |  | ​
Contractual interest expense | $ | 1,110 | ​ | $ | 1,110 | ​ | ​
Amortization of debt issuance costs |  | 181 | ​ |  | 175 | ​ | ​
Total | $ | 1,291 | ​ | $ | 1,285 | ​ | ​
Effective interest rate of the liability component |  | 3.5 | % |  | 3.5 | % | ​

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- Definition Tabular disclosure of activity related to the liability resulting from the sale of future royalties. + References No definition available. + Details
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