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Stock award plan - Narrative (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended
Dec. 31, 2020
Jun. 30, 2016
May 31, 2013
Mar. 31, 2022
Mar. 31, 2021
Apr. 30, 2022
Jun. 30, 2021
May 31, 2021
Jan. 31, 2020
Stock option plan                  
Share-based compensation expense       $ 26,589 $ 25,707        
Unrecognized compensation cost       $ 251,800          
Weighted average remaining service period for recognition of unrecognized compensation cost       2 years 7 months 13 days          
Unvested restricted stock                  
Stock option plan                  
Granted (in shares)       1,490,190          
Forfeited (in shares)       68,570          
Stock option                  
Stock option plan                  
Granted (in shares)       1,275,830          
Forfeited (in shares)       199,511          
Expected dividend yield (as a percent)       0.00%          
Weighted average grant date fair value (in dollars per share)       $ 23.92          
Employee Stock [Member]                  
Stock option plan                  
Number of shares authorized (in shares)             2,000,000 1,000,000  
Award requisite service period   6 months              
Purchase price of common stock, percent   85.00%              
Employee stock purchase plan, voting percentage limit   5.00%              
Share-based compensation expense       $ 500          
1998 Employee, Director, and Consultant Stock Option Plan, 2009 Equity and Long-term Incentive Plan, and 2013 Stock Incentive Plan | Common stock                  
Stock option plan                  
Number of shares available for issuance       0          
1998 Employee, Director, and Consultant Stock Option Plan, 2009 Equity and Long-term Incentive Plan, and 2013 Stock Incentive Plan | Common stock | Maximum                  
Stock option plan                  
Number of shares subject to outstanding awards (in shares)     3,040,444            
2009 Equity and Long Term Incentive Plan and 2013 Stock Incentive Plan | Common stock                  
Stock option plan                  
Number of shares available for issuance     122,296            
2013 Long Term Incentive Plan | Minimum                  
Stock option plan                  
Share based Compensation Arrangement by Share based Payment Award Number of Shares Authorized Annual Increase Number     2,500,000            
Annual increase in the number of shares outstanding on the first day of the fiscal year     4.00%            
2013 Long Term Incentive Plan | Common stock                  
Stock option plan                  
Number of shares available for issuance       922,076          
2020 Inducement Stock Incentive Plan                  
Stock option plan                  
Number of shares authorized (in shares)           1,300,000      
Vesting period       4 years          
2020 Inducement Stock Incentive Plan | Maximum                  
Stock option plan                  
Expiration period       10 years          
2020 Inducement Stock Incentive Plan | Common stock                  
Stock option plan                  
Number of shares available for issuance       823,211          
Number of additional shares authorized (in shares) 1,000,000                
2020 Inducement Stock Incentive Plan | Common stock | Maximum                  
Stock option plan                  
Number of shares authorized (in shares)                 1,000,000
2020 Inducement Stock Incentive Plan | Stock option                  
Stock option plan                  
Stockholder's specified ownership percentage       10.00%          
Inducement grants for non-statutory stock options (in shares)       18,255          
2020 Inducement Stock Incentive Plan | Stock option | Minimum                  
Stock option plan                  
Stock options granted, exercise price as percentage of the fair market value of common stock at grant date       100.00%          
2020 Inducement Stock Incentive Plan | Stock option | Maximum                  
Stock option plan                  
Stock options granted to stockholder with specified ownership percentage, exercise price as percentage of the fair market value of common stock at grant date       110.00%          
2020 Inducement Stock Incentive Plan | Restricted stock units                  
Stock option plan                  
Granted (in shares)       10,675