XML 78 R66.htm IDEA: XBRL DOCUMENT v3.22.1
Intangible assets and goodwill - Narrative (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended 43 Months Ended
Apr. 20, 2017
Aug. 31, 2021
Dec. 31, 2019
May 31, 2019
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2018
Dec. 31, 2019
Mar. 31, 2022
Dec. 31, 2021
Apr. 29, 2020
Aug. 23, 2018
Finite-Lived Intangible Assets                        
Amortization of intangible assets         $ 23,473 $ 11,278            
Total allocation of IPR&D assets         576,500              
Change in indefinite-lived intangibles                 $ 0      
Accrued royalties         30,670       30,670 $ 35,679    
Goodwill         82,341       82,341 $ 82,341    
Changes in goodwill                 0      
Tegsedi                        
Finite-Lived Intangible Assets                        
Royalty payments         $ 400 0            
Accrued royalties           500            
Weighted Average [Member]                        
Finite-Lived Intangible Assets                        
Remaining amortization period         2 years 2 months 12 days              
Akcea                        
Finite-Lived Intangible Assets                        
Milestone payments   $ 4,000                    
Marathon                        
Finite-Lived Intangible Assets                        
Milestone payments received         $ 50,000       50,000      
Agilis                        
Finite-Lived Intangible Assets                        
Development milestone payments which the entity is obligated to pay         40,000       40,000   $ 40,000  
Goodwill                       $ 82,300
Goodwill adjustment             $ 18,000          
Agilis Merger Agreement | Akcea                        
Finite-Lived Intangible Assets                        
Milestone payments     $ 4,000 $ 6,000 4,000     $ 6,000        
Useful life     10 years                  
Agilis Merger Agreement | Marathon                        
Finite-Lived Intangible Assets                        
Development milestone payments which the entity is obligated to pay         50,000       50,000      
Emflaza asset acquisition                        
Finite-Lived Intangible Assets                        
Finite-lived intangibles $ 148,400                      
Milestone obligation payments recorded         62,100 $ 8,900            
Useful life 7 years                      
Emflaza asset acquisition | Accounts payable and accrued expenses                        
Finite-Lived Intangible Assets                        
Milestone payable         $ 12,100       $ 12,100