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Debt - (Tables) | 6 Months Ended
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Jun. 30, 2022
Debt Instrument, Redemption [Line Items] |
Summary of liability for sale of future royalties | ​
​ | ​ | ​ | ​ | ​
​ |  | Six Months Ended June 30, | ​
Liability for sale of future royalties- (current and noncurrent) | ​ | 2022 | ​
Beginning balance as of December 31, 2021 | ​ | $ | 733,985 | ​
Less: Non-cash royalty revenue payable to RPI | ​ | ​ | (17,482) | ​
Plus: Non-cash interest expense recognized | ​ | ​ | 37,825 | ​
Ending balance | ​ | $ | 754,328 | ​
Effective interest rate as of June 30, 2022 | ​ |  | 10.1 | %
1.50% Convertible senior notes due 2026 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ | ​ | ​ | ​ | ​ | ​
Liability component | ​ | June 30, 2022 | ​ | December 31, 2021 | ​
Principal | ​ | $ | 287,500 | ​ | $ | 287,500 | ​
Less: Debt issuance costs | ​ |  | (5,040) | ​ |  | (5,606) | ​
Net carrying amount | ​ | $ | 282,460 | ​ | $ | 281,894 | ​
Summary of interest expense recognized related to the Convertible Notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ |
​ | ​ | Three Months Ended June 30, | ​ | Six Months Ended June 30, | ​
​ | ​ | 2022 | ​ | 2021 |  | 2022 | ​ | 2021 | ​
Contractual interest expense | ​ | $ | 1,066 | ​ | $ | 1,066 | ​ | $ | 2,135 | ​ | $ | 2,135 | ​
Amortization of debt issuance costs | ​ |  | 284 | ​ | ​ | 279 | ​ | ​ | 567 | ​ | ​ | 556 | ​
Total | ​ | $ | 1,350 | ​ | $ | 1,345 | ​ | $ | 2,702 | ​ | $ | 2,691 | ​
Effective interest rate of the liability component | ​ |  | 1.9 | % | ​ | 1.9 | % | ​ | 1.9 | % | ​ | 1.9 | %
3.00% Convertible senior notes due 2022 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Liability component |  | June 30, 2022 |  | December 31, 2021 | ​
Principal | ​ | $ | 150,000 | ​ | $ | 150,000 | ​
Less: Debt issuance costs | ​ |  | (92) | ​ |  | (460) | ​
Net carrying amount | ​ | $ | 149,908 | ​ | $ | 149,540 | ​
Summary of interest expense recognized related to the Convertible Notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​ | ​ | ​ |  | ​
​ | ​ | Three Months Ended June 30, |  | Six Months Ended June 30, |  | ​
​ |  | 2022 |  | 2021 |  | 2022 |  | 2021 |  | ​
Contractual interest expense | ​ | $ | 1,131 | ​ | $ | 1,131 | ​ | $ | 2,241 | ​ | $ | 2,241 | ​ | ​
Amortization of debt issuance costs | ​ |  | 186 | ​ |  | 180 | ​ |  | 368 | ​ |  | 355 | ​ | ​
Total | ​ | $ | 1,317 | ​ | $ | 1,311 | ​ | $ | 2,609 | ​ | $ | 2,596 | ​ | ​
Effective interest rate of the liability component | ​ |  | 3.5 | % |  | 3.5 | % |  | 3.5 | % |  | 3.5 | % | ​

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