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v3.22.2.2

Debt - (Tables) | 9 Months Ended
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Sep. 30, 2022
Debt Instrument, Redemption [Line Items] |
Summary of liability for sale of future royalties | ​
​ | ​ | ​ | ​ | ​
​ |  | Nine Months Ended September 30, | ​
Liability for sale of future royalties- (current and noncurrent) | ​ | 2022 | ​
Beginning balance as of December 31, 2021 | ​ | $ | 733,985 | ​
Less: Non-cash royalty revenue payable to RPI | ​ | ​ | (31,617) | ​
Plus: Non-cash interest expense recognized | ​ | ​ | 55,778 | ​
Ending balance | ​ | $ | 758,146 | ​
Effective interest rate as of September 30, 2022 | ​ |  | 9.4 | %
1.50% Convertible senior notes due 2026 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ | ​ | ​ | ​ | ​ | ​
Liability component | ​ | September 30, 2022 | ​ | December 31, 2021 | ​
Principal | ​ | $ | 287,500 | ​ | $ | 287,500 | ​
Less: Debt issuance costs | ​ |  | (4,751) | ​ |  | (5,606) | ​
Net carrying amount | ​ | $ | 282,749 | ​ | $ | 281,894 | ​
Summary of interest expense recognized related to the Convertible Notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ |
​ | ​ | Three Months Ended September 30, | ​ | Nine Months Ended September 30, | ​
​ | ​ | 2022 | ​ | 2021 |  | 2022 | ​ | 2021 | ​
Contractual interest expense | ​ | $ | 1,081 | ​ | $ | 1,081 | ​ | $ | 3,217 | ​ | $ | 3,217 | ​
Amortization of debt issuance costs | ​ |  | 289 | ​ | ​ | 283 | ​ | ​ | 856 | ​ | ​ | 839 | ​
Total | ​ | $ | 1,370 | ​ | $ | 1,364 | ​ | $ | 4,073 | ​ | $ | 4,056 | ​
Effective interest rate of the liability component | ​ |  | 1.9 | % | ​ | 1.9 | % | ​ | 1.9 | % | ​ | 1.9 | %
3.00% Convertible senior notes due 2022 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Liability component |  | September 30, 2022 |  | December 31, 2021 | ​
Principal | ​ | $ | 150,000 | ​ | $ | 150,000 | ​
Less: Debt issuance costs | ​ |  | — | ​ |  | (460) | ​
Repayment of Convertible Notes | ​ |  | (150,000) | ​ |  | — | ​
Net carrying amount | ​ | $ | — | ​ | $ | 149,540 | ​
Summary of interest expense recognized related to the Convertible Notes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​ | ​ | ​ |  | ​
​ | ​ | Three Months Ended September 30, |  | Nine Months Ended September 30, |  | ​
​ |  | 2022 |  | 2021 |  | 2022 |  | 2021 |  | ​
Contractual interest expense | ​ | $ | 559 | ​ | $ | 1,134 | ​ | $ | 2,800 | ​ | $ | 3,375 | ​ | ​
Amortization of debt issuance costs | ​ |  | 92 | ​ |  | 182 | ​ |  | 460 | ​ |  | 538 | ​ | ​
Total | ​ | $ | 651 | ​ | $ | 1,316 | ​ | $ | 3,260 | ​ | $ | 3,913 | ​ | ​
Effective interest rate of the liability component | ​ |  | 3.5 | % |  | 3.5 | % |  | 3.5 | % |  | 3.5 | % | ​

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