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v3.22.2.2

Summary of significant accounting policies - Narrative (Details) $ in Thousands |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | ---
Dec. 22, 2017 | Jun. 30, 2022 USD ($) | Jul. 31, 2020 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) segment | Sep. 30, 2021 USD ($) | Dec. 31, 2019 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2018 USD ($)
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Number of operating segments | segment |  |  |  |  |  | 1 |  |  |  |
Allowance for credit loss |  |  |  | $ 0 | $ 0 | $ 0 | $ 0 |  |  |
Increase in allowance for credit losses |  |  |  | 0 | 0 | 0 | 0 |  |  |
Allowance for doubtful accounts receivable |  |  |  | 100 |  | 100 |  |  | $ 100 |
Revenue |  |  |  | 217,127 | 138,743 | 531,389 | 373,364 |  |  |
Deferred payroll taxes provided for under CARES Act |  |  |  |  |  | 1,300 |  |  |  |
Cash consideration received from Royalty Purchase Agreement |  |  | $ 650,000 |  |  |  |  |  |  |
Income taxes |  |  |  |  |  |  |  |  |  |
Federal income tax statutory rate | 21.00% |  |  |  |  |  |  |  |  |
State income tax provision - IRC Section 174 R&D Expenses |  |  |  |  |  | 8,700 |  |  |  |
Income tax benefit from release of valuation allowance on IPR&D intangible assets |  |  |  |  |  | 18,900 |  |  |  |
Agilis |  |  |  |  |  |  |  |  |  |
Income taxes |  |  |  |  |  |  |  |  |  |
Deferred tax liability |  |  |  |  |  |  |  |  |  | $ 122,000
Deposits and other assets |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Bank guarantee |  |  |  | 500 |  | 500 |  |  |  |
Hopewell Campus |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Period after which letter of credit may be reduced if lease is not in default |  |  |  |  |  |  |  | 5 years |  |
Hopewell Campus | Minimum |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Term for letter of credit (in years) |  |  |  |  |  |  |  | 5 years |  |
Hopewell Campus | Deposits and other assets |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Letters of credit |  |  |  |  |  |  |  | $ 7,500 |  |
Hopewell Campus | Fifth Anniversary |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Letters of credit |  |  |  |  |  |  |  | $ 3,800 |  |
Warren Premises |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Period after which letter of credit may be reduced if lease is not in default |  | 5 years |  |  |  |  |  |  |  |
Warren Premises | Deposits and other assets |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Letters of credit |  | $ 8,100 |  |  |  |  |  |  |  |
Warren Premises | Fifth Anniversary |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Letters of credit |  | $ 4,100 |  |  |  |  |  |  |  |
Net product revenue |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  | 134,186 | 115,605 | 407,720 | 309,998 |  |  |
Net product revenue | Non-US |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  | 79,400 | 68,500 | 247,600 | 170,200 |  |  |
Emflaza | United States |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  | 54,800 | 47,100 | 160,100 | 139,800 |  |  |
Translarna | Non-US |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  | $ 76,600 | $ 67,200 | $ 232,900 | $ 166,300 |  |  |

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