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Fair value of financial instruments and investments - Available-for-sale securities (Details) - USD ($) $ in Thousands | Sep. 30, 2022 | Dec. 31, 2021
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Debt Securities, Available-for-sale [Line Items] |  |
Securities in an unrealized loss position less than 12 months - Unrealized losses | $ (2,347) | $ (673)
Securities in an unrealized loss position less than 12 months - Fair Value | 55,290 | 256,801
Securities in an unrealized loss position greater than 12 months - Unrealized losses | (587) | (36)
Securities in an unrealized loss position greater than 12 months - Fair Value | 15,710 | 4,985
Total - Unrealized losses | (2,934) | (709)
Total - Fair Value | 71,000 | 261,786
Commercial paper |  |
Debt Securities, Available-for-sale [Line Items] |  |
Securities in an unrealized loss position less than 12 months - Unrealized losses |  | (1)
Securities in an unrealized loss position less than 12 months - Fair Value |  | 12,992
Total - Unrealized losses |  | (1)
Total - Fair Value |  | 12,992
Corporate debt securities |  |
Debt Securities, Available-for-sale [Line Items] |  |
Securities in an unrealized loss position less than 12 months - Unrealized losses | (2,143) | (608)
Securities in an unrealized loss position less than 12 months - Fair Value | 50,497 | 217,540
Securities in an unrealized loss position greater than 12 months - Unrealized losses | (550) | (36)
Securities in an unrealized loss position greater than 12 months - Fair Value | 14,871 | 4,985
Total - Unrealized losses | (2,693) | (644)
Total - Fair Value | 65,368 | 222,525
Asset-backed securities |  |
Debt Securities, Available-for-sale [Line Items] |  |
Securities in an unrealized loss position less than 12 months - Unrealized losses |  | (5)
Securities in an unrealized loss position less than 12 months - Fair Value |  | 10,786
Total - Unrealized losses |  | (5)
Total - Fair Value |  | 10,786
Government obligations |  |
Debt Securities, Available-for-sale [Line Items] |  |
Securities in an unrealized loss position less than 12 months - Unrealized losses | (204) | (59)
Securities in an unrealized loss position less than 12 months - Fair Value | 4,793 | 15,483
Securities in an unrealized loss position greater than 12 months - Unrealized losses | (37) |
Securities in an unrealized loss position greater than 12 months - Fair Value | 839 |
Total - Unrealized losses | (241) | (59)
Total - Fair Value | $ 5,632 | $ 15,483

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