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Debt - (Tables) | 12 Months Ended
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Dec. 31, 2022
Debt Instrument, Redemption [Line Items] |
Summary of liability for sale of future royalties | The following table shows the activity within the “liability for sale of future royalties- current” and “liability for sale of future royalties- noncurrent” accounts for the year ended December 31, 2022: ​
​ | ​ | ​ | ​ | ​
​ |  | Year Ended December 31, | ​
Liability for sale of future royalties- (current and noncurrent) | ​ | 2022 | ​
Beginning balance as of December 31, 2021 | ​ | $ | 733,985 | ​
Less: Non-cash royalty revenue payable to RPI | ​ | ​ | (48,738) | ​
Plus: Non-cash interest expense recognized | ​ | ​ | 72,639 | ​
Ending balance | ​ | $ | 757,886 | ​
Effective interest rate as of December 31, 2022 | ​ |  | 8.7 | %
​
1.50% Convertible senior notes due 2026 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | The 2026 Convertible Notes consist of the following: ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | Year ended December 31,
Liability component | ​ | 2022 | ​ | ​ | 2021
Principal | ​ | $ | 287,500 | ​ | $ | 287,500
Less: Debt issuance costs | ​ |  | (4,456) | ​ | ​ | (5,606)
Net carrying amount | ​ | $ | 283,044 | ​ | $ | 281,894
​
Summary of interest expense recognized related to debt | The following table sets forth total interest expense recognized related to the 2026 Convertible Notes: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | Year ended | ​
​ | ​ | December 31, | ​
​ | ​ | 2022 | ​ | 2021 | ​
Contractual interest expense | ​ | $ | 4,313 | ​ | $ | 4,313 | ​
Amortization of debt issuance costs | ​ |  | 1,150 | ​ | ​ | 1,128 | ​
Total | ​ | $ | 5,463 | ​ | $ | 5,441 | ​
Effective interest rate | ​ |  | 1.9 | % | ​ | 1.9 | %
​
3.00% Convertible senior notes due 2022 |
Debt Instrument, Redemption [Line Items] |
Summary of convertible notes | The 2022 Convertible Notes consisted of the following: ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year ended
​ | ​ | December 31,
Liability component | ​ | 2022 |  | 2021
Principal | ​ | $ | 150,000 | ​ | $ | 150,000
Less: Debt issuance costs | ​ |  | — | ​ |  | (460)
Repayment of Convertible Notes | ​ |  | (150,000) | ​ |  | —
Net carrying amount | ​ | $ | — | ​ | $ | 149,540
​
Summary of interest expense recognized related to debt | The following table sets forth total interest expense recognized related to the 2022 Convertible Notes: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year ended |
​ | ​ | December 31, |
​ | ​ | 2022 |  | 2021 |
Contractual interest expense | ​ | $ | 2,800 | ​ | $ | 4,500 | ​
Amortization of debt issuance costs | ​ |  | 460 | ​ |  | 720 | ​
Total | ​ | $ | 3,260 | ​ | $ | 5,220 | ​
Effective interest rate | ​ |  | 3.5 | % |  | 3.5 | %
Senior Secured Term Loan Facility |
Debt Instrument, Redemption [Line Items] |
Summary of interest expense recognized related to debt | The following table sets forth total interest expense recognized related to the senior secured term loan: ​
​ | ​ | ​ | ​
​ | Year ended
​ | December 31,
​ | 2022 | ​
Contractual interest expense | $ | 6,069 | ​
Amortization of debt issuance costs |  | 290 | ​
Total | $ | 6,359 | ​
Effective interest rate | ​ | 12.2 | %
​

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