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Debt - Liability for Sale of Future Royalties (Details) - USD ($) $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Jul. 31, 2020 | Dec. 31, 2022 | Dec. 31, 2020
Debt Disclosure [Abstract] |  |  |
Proceeds from sale of future royalties | $ 650,000 |  | $ 650,000
Beginning balance |  | $ 733,985 |
Less: Non-cash royalty revenue payable to RPI |  | (48,738) |
Plus: non-cash interest expense recognized |  | 72,639 |
Ending balance |  | $ 757,886 |
Effective interest rate of the liability component | 11.00% | 8.70% |

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- Definition Amount of liabilities related to the sale of future royalties. + References No definition available. + Details
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Balance Type: | credit
Period Type: | instant

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- Definition Amount of interest expense recognized related to the liability for the sale of future royalties per terms of the agreement. + References No definition available. + Details
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Data Type: | xbrli:monetaryItemType
Balance Type: | credit
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X
- Definition Amount of royalty revenue recognized during the period relating to the sale of future royalties payable under terms of the agreement. + References No definition available. + Details
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Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

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- Definition Cash received for sale of future royalties during the current period. + References No definition available. + Details
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Namespace Prefix: | ptct_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

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- Definition Effective interest rate for the funds borrowed under the debt agreement considering interest compounding and original issue discount or premium. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 20 -Section 50 -Paragraph 6 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=123466204&loc=SL6036836-161870 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 835 -SubTopic 30 -Section 45 -Paragraph 2 -URI https://asc.fasb.org/extlink&oid=124435984&loc=d3e28551-108399 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 835 -SubTopic 30 -Section 50 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=124429444&loc=SL124452920-239629 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.22(a)(1)) -URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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