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Leases - Narrative (Details) $ in Thousands |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Jul. 01, 2020 USD ($) ft² item | May 31, 2022 USD ($) ft² building period | Dec. 31, 2022 USD ($) ft² lease | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Jun. 19, 2020 USD ($)
Leases |  |  |  |  |  |
Operating lease, expense |  |  | $ 25,200 | $ 21,400 | $ 15,300 |
Finance Lease, Liability |  |  | 21,675 |  |  |
Finance lease liabilities- current |  |  | 3,000 | 3,000 |  |
Finance lease liabilities- noncurrent |  |  | 18,675 | 20,053 |  |
Aggregate rent, Initial term |  |  | 268,037 |  |  |
Operating lease ROU assets |  |  | 102,430 | 77,421 |  |
Operating Lease, Liability |  |  | 110,230 |  |  |
Research and development |  |  | 651,496 | 540,684 | 477,643 |
2023 |  |  | 15,373 |  |  |
MassBio |  |  |  |  |  |
Leases |  |  |  |  |  |
Finance lease cost |  |  | $ 1,600 | $ 1,700 |  |
Finance Lease, Liability |  |  |  |  |  | $ 41,400
Finance lease ROU asset |  |  |  |  |  | $ 41,400
Finance lease, term of contract |  |  |  |  |  | 12 years 6 months
Research and development |  |  |  |  | $ 41,400 |
Minimum |  |  |  |  |  |
Leases |  |  |  |  |  |
Operating lease, term of contract |  |  | 1 year 2 months 12 days |  |  |
Maximum |  |  |  |  |  |
Leases |  |  |  |  |  |
Operating lease, term of contract |  |  | 16 years 4 months 24 days |  |  |
Renewal term |  |  | 15 years |  |  |
Principal Office - NJ |  |  |  |  |  |
Leases |  |  |  |  |  |
Number of operating leases | lease |  |  | 2 |  |  |
Lessee, Operating Lease, Existence of Option to Terminate [true false] |  |  | false |  |  |
New Building | Minimum |  |  |  |  |  |
Leases |  |  |  |  |  |
Area of real estate property | ft² |  |  | 75,000 |  |  |
Hopewell Campus |  |  |  |  |  |
Leases |  |  |  |  |  |
Operating lease, term of contract | 15 years |  |  |  |  |
Area of real estate property | ft² | 220,500 |  |  |  |  |
Renewal term | 10 years |  |  |  |  |
Number of renewable terms | item | 2 |  |  |  |  |
Lessee, Operating Lease, Existence of Option to Extend [true false] | true |  |  |  |  |
Aggregate rent, Initial term | $ 111,500 |  |  |  |  |
Percent of market rate | 95.00% |  |  |  |  |
Warren Premises |  |  |  |  |  |
Leases |  |  |  |  |  |
Operating lease, term of contract |  | 17 years |  |  |  |
Number of buildings leased | building |  | 2 |  |  |  |
Area of real estate property | ft² |  | 360,000 |  |  |  |
Renewal term |  | 5 years |  |  |  |
Number of renewable terms | period |  | 3 |  |  |  |
Lessee, Operating Lease, Existence of Option to Extend [true false] |  | true |  |  |  |
Aggregate rent, Initial term |  | $ 163,000 |  |  |  |
Operating lease ROU assets |  | 28,900 |  |  |  |
Operating Lease, Liability |  | $ 28,900 |  |  |  |
Base rent abatement period |  | 3 years |  |  |  |
Base rent abatement |  | $ 18,600 |  |  |  |
Aggregate rent net of base rate abatement, initial term |  | 144,400 |  |  |  |
Allowance for lease improvements |  | 36,200 |  |  |  |
Commitment to fund construction account |  | 3,600 |  |  |  |
Payment due from lessor at issuance of temporary certificate of occupancy |  | $ 5,000 |  |  |  |

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