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Net loss per share | 12 Months Ended
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Dec. 31, 2022
Earnings Per Share [Abstract] |
Net loss per share | 10. Net loss per share Basic and diluted net loss per share is computed by dividing net loss available to common stockholders by the weighted-average number of common shares outstanding. Potentially dilutive securities were excluded from the diluted calculation because their effect would be anti-dilutive. The following table sets forth the computation of basic and diluted net loss per share for common stockholders: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year ended December 31, | ​
​ | ​ | 2022 |  | 2021 |  | 2020 | ​
Numerator | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Net loss | ​ | $ | (559,017) |  | $ | (523,901) |  | $ | (438,160) |
Denominator | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ |
Denominator for basic and diluted net loss per share | ​ |  | 71,728,634 |  |  | 70,466,393 |  |  | 66,027,908 |
Net loss per share: | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ |
Basic and diluted | ​ | $ | (7.79) | * | $ | (7.43) | * | $ | (6.64) | *
* | For the years ended December 31, 2022, 2021, and 2020, the Company experienced a net loss and therefore did not report any dilutive share impact.
The following table shows historical dilutive common share equivalents outstanding, which are not included in the above historical calculation, as the effect of their inclusion is anti-dilutive during each period. ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | As of December 31,
​ |  | 2022 |  | 2021 |  | 2020
Stock Options | ​ | 11,502,417 | ​ | 10,772,582 | ​ | 9,663,677
Unvested restricted stock awards and units |  | 2,516,336 |  | 1,519,831 |  | 982,058
Total |  | 14,018,753 |  | 12,292,413 |  | 10,645,735
​

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