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Debt - (Tables)

12 Months Ended

Dec. 31, 2022

Debt Instrument, Redemption [Line Items]

Summary of liability for sale of future royalties

The following table shows the activity within the “liability for sale of future royalties- current” and “liability for sale of future royalties- noncurrent” accounts for the year ended December 31, 2022:

​

​	​	​	​	​
​		Year Ended December 31,		​
Liability for sale of future royalties- (current and noncurrent)	​	2022		​
Beginning balance as of December 31, 2021	​	$	733,985	​
Less: Non-cash royalty revenue payable to RPI	​	​	(48,738)	​
Plus: Non-cash interest expense recognized	​	​	72,639	​
Ending balance	​	$	757,886	​
Effective interest rate as of December 31, 2022	​		8.7	%

​

1.50% Convertible senior notes due 2026

Debt Instrument, Redemption [Line Items]

Summary of convertible notes

The 2026 Convertible Notes consist of the following:

​

​	​	​	​	​	​	​
​	​	​	Year ended  December 31,
Liability component	​	2022		​	​	2021
Principal	​	$	287,500	​	$	287,500
Less: Debt issuance costs	​		(4,456)	​	​	(5,606)
Net carrying amount	​	$	283,044	​	$	281,894

​

Summary of interest expense recognized related to debt

The following table sets forth total interest expense recognized related to the 2026 Convertible Notes:

​

​	​	​	​	​	​	​	​
​		Year ended					​
​	​	December 31,					​
​	​	2022		​	2021		​
Contractual interest expense	​	$	4,313	​	$	4,313	​
Amortization of debt issuance costs	​		1,150	​	​	1,128	​
Total	​	$	5,463	​	$	5,441	​
Effective interest rate	​		1.9	%	​	1.9	%

​

3.00% Convertible senior notes due 2022

Debt Instrument, Redemption [Line Items]

Summary of convertible notes

The 2022 Convertible Notes consisted of the following:

​

​	​	​	​	​	​	​
​	​	Year ended
​	​	December 31,
Liability component	​	2022			2021
Principal	​	$	150,000	​	$	150,000
Less: Debt issuance costs	​		—	​		(460)
Repayment of Convertible Notes	​		(150,000)	​		—
Net carrying amount	​	$	—	​	$	149,540

​

Summary of interest expense recognized related to debt

The following table sets forth total interest expense recognized related to the 2022 Convertible Notes:

​

​	​	​	​	​	​	​	​
​	​	Year ended
​	​	December 31,
​	​	2022			2021
Contractual interest expense	​	$	2,800	​	$	4,500	​
Amortization of debt issuance costs	​		460	​		720	​
Total	​	$	3,260	​	$	5,220	​
Effective interest rate	​		3.5	%		3.5	%

Senior Secured Term Loan Facility

Debt Instrument, Redemption [Line Items]

Summary of interest expense recognized related to debt

The following table sets forth total interest expense recognized related to the senior secured term loan:

​

​	​	​	​
​	Year ended
​	December 31,
​	2022		​
Contractual interest expense	$	6,069	​
Amortization of debt issuance costs		290	​
Total	$	6,359	​
Effective interest rate	​	12.2	%

​

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