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Intangible assets and goodwill - (Tables)

12 Months Ended

Dec. 31, 2022

Goodwill and Intangible Assets Disclosure [Abstract]

Schedule of definite lived intangible assets

Definite lived intangible assets consisted of the following at December 31, 2022 and 2021:

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Ending Balance at

​

​

​

​

​

Reclass from

​

​

​

​

​

Foreign

​

​

Ending Balance at

Definite lived

​

​

December 31,

​

​

​

​

​

Indefinite Lived to

​

​

​

​

​

currency

​

​

December 31,

intangibles assets, gross

​

2021

​

Additions

​

Definite Lived

​

Impairment

​

translation

​

2022

Emflaza

​

$

291,875

​

$

128,378

​

$

—

​

$

—

​

$

—

​

$

420,253

Waylivra

​

​

9,904

​

​

—

​

​

—

​

​

—

​

​

(588)

​

​

9,316

Tegsedi

​

​

4,060

​

​

3,240

​

​

—

​

​

—

​

​

(191)

​

​

7,109

Upstaza

​

​

—

​

​

—

​

​

89,550

​

​

—

​

​

—

​

​

89,550

Total definite lived intangibles, gross

​

$

305,839

​

$

131,618

​

$

89,550

​

$

—

​

$

(779)

​

$

526,228

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Ending Balance at

​

​

​

​

​

Foreign

​

​

Ending Balance at

Definite lived

​

​

December 31,

​

​

​

​

​

currency

​

​

December 31,

intangibles assets, accumulated amortization

​

2021

​

Amortization

​

translation

​

2022

Emflaza

​

$

(154,594)

​

$

(111,429)

​

$

—

​

$

(266,023)

Waylivra

​

​

(1,821)

​

​

(1,020)

​

​

90

​

​

(2,751)

Tegsedi

​

​

(1,083)

​

​

(685)

​

​

59

​

​

(1,709)

Upstaza

​

​

—

​

​

(3,420)

​

​

—

​

​

(3,420)

Total definite lived intangibles, accumulated amortization

​

$

(157,498)

​

$

(116,554)

​

$

149

​

$

(273,903)

​

​

​

​

​

​

​

​

​

​

​

​

​

Total definite lived intangibles, net

​

​

​

​

​

​

​

​

​

​

$

252,325

​

Schedule of estimated future amortization of intangible assets

The estimated future amortization of the Emflaza rights, Waylivra, Tegsedi, and Upstaza intangible assets is expected to be as follows:

​

​	​	​	​
​		As of December 31, 2022
2023	​	$	142,324
2024	​		30,609
2025	​		9,352
2026	​		9,352
2027 and thereafter	​		60,688
Total	​	$	252,325

​

Schedule of indefinite lived intangible assets

Indefinite lived intangible assets consisted of the following at December 31, 2022 and 2021:

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Ending Balance at

​

​

​

​

​

Reclass from

​

​

​

​

​

Foreign

​

​

Ending Balance at

Indefinite lived

​

​

December 31,

​

​

​

​

​

Indefinite Lived to

​

​

​

​

​

currency

​

​

December 31,

intangibles assets

​

2021

​

Additions

​

Definite Lived

​

Impairment

​

translation

​

2022

Upstaza

​

$

358,700

​

$

—

​

$

(89,550)

​

$

(33,384)

​

$

—

​

$

235,766

PTC-FA

​

​

112,500

​

​

—

​

​

—

​

​

—

​

​

—

​

​

112,500

PTC-AS

​

​

105,300

​

​

—

​

​

—

​

​

—

​

​

—

​

​

105,300

Total indefinite lived intangibles

​

$

576,500

​

$

—

​

$

(89,550)

​

$

(33,384)

​

$

—

​

$

453,566

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Total intangible assets, net

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

$

705,891

​

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- References

No definition available.

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- Definition

Tabular disclosure of assets, excluding financial assets and goodwill, lacking physical substance with a finite life, by either major class or business segment.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph (a)
-URI https://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 1
-Subparagraph (a)
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Tabular disclosure of assets, excluding financial assets and goodwill, lacking physical substance and exist in perpetuity, by either major class or business segment.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 3
-Subparagraph (b),(d)
-URI https://asc.fasb.org/extlink&oid=66006027&loc=d3e16373-109275

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph (b)
-URI https://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

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- Definition

Tabular disclosure of the amount of amortization expense expected to be recorded in succeeding fiscal years for finite-lived intangible assets.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 50
-Paragraph 2
-Subparagraph (a)
-URI https://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275

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