Fixed assets (Details) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Fixed assets
Gross fixed assets	$ 109,958	$ 79,758
Less accumulated depreciation and amortization	(37,368)	(27,173)
Property, Plant and Equipment, Net, Total	72,590	52,585
Depreciation and amortization	12,300	9,400	$ 6,600
Leasehold improvements
Fixed assets
Gross fixed assets	28,969	19,937
Computer equipment and software
Fixed assets
Gross fixed assets	15,332	13,812
Machinery and lab equipment
Fixed assets
Gross fixed assets	47,496	33,187
Furniture and fixtures
Fixed assets
Gross fixed assets	3,812	3,805
Assets in process
Fixed assets
Gross fixed assets	$ 14,349	$ 9,017

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation.

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