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Leases - Narrative (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Jul. 01, 2020
USD ($)
ft²
item
May 31, 2022
USD ($)
ft²
building
period
Dec. 31, 2022
USD ($)
ft²
lease
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Jun. 19, 2020
USD ($)
Leases            
Operating lease, expense     $ 25,200 $ 21,400 $ 15,300  
Finance Lease, Liability     21,675      
Finance lease liabilities- current     3,000 3,000    
Finance lease liabilities- noncurrent     18,675 20,053    
Aggregate rent, Initial term     268,037      
Operating lease ROU assets     102,430 77,421    
Operating Lease, Liability     110,230      
Research and development     651,496 540,684 477,643  
2023     15,373      
MassBio            
Leases            
Finance lease cost     $ 1,600 $ 1,700    
Finance Lease, Liability           $ 41,400
Finance lease ROU asset           $ 41,400
Finance lease, term of contract           12 years 6 months
Research and development         $ 41,400  
Minimum            
Leases            
Operating lease, term of contract     1 year 2 months 12 days      
Maximum            
Leases            
Operating lease, term of contract     16 years 4 months 24 days      
Renewal term     15 years      
Principal Office - NJ            
Leases            
Number of operating leases | lease     2      
Lessee, Operating Lease, Existence of Option to Terminate [true false]     false      
New Building | Minimum            
Leases            
Area of real estate property | ft²     75,000      
Hopewell Campus            
Leases            
Operating lease, term of contract 15 years          
Area of real estate property | ft² 220,500          
Renewal term 10 years          
Number of renewable terms | item 2          
Lessee, Operating Lease, Existence of Option to Extend [true false] true          
Aggregate rent, Initial term $ 111,500          
Percent of market rate 95.00%          
Warren Premises            
Leases            
Operating lease, term of contract   17 years        
Number of buildings leased | building   2        
Area of real estate property | ft²   360,000        
Renewal term   5 years        
Number of renewable terms | period   3        
Lessee, Operating Lease, Existence of Option to Extend [true false]   true        
Aggregate rent, Initial term   $ 163,000        
Operating lease ROU assets   28,900        
Operating Lease, Liability   $ 28,900        
Base rent abatement period   3 years        
Base rent abatement   $ 18,600        
Aggregate rent net of base rate abatement, initial term   144,400        
Allowance for lease improvements   36,200        
Commitment to fund construction account   3,600        
Payment due from lessor at issuance of temporary certificate of occupancy   $ 5,000