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Fair value of financial instruments and investments - Hierarchy (Details) - USD ($) $ in Thousands | Mar. 31, 2023 | Dec. 31, 2022
--- | --- | ---
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities - available for sale | $ 10,249 | $ 22,610
Contingent consideration payable | 166,400 | 164,000
Transfers of assets measured between Level 1, Level 2, and Level 3 | 0 | 0
Recurring basis |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
ClearPoint Equity Investments | 10,926 | 10,965
ClearPoint convertible debt security | 15,290 | 15,231
Recurring basis | Quoted prices in active markets for identical assets (Level 1) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
ClearPoint Equity Investments | 10,926 | 10,965
Recurring basis | Significant other observable inputs (Level 2) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
ClearPoint convertible debt security | 15,290 | 15,231
Recurring basis | Development and Regulatory Milestones |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable | 85,500 | 82,500
Recurring basis | Development and Regulatory Milestones | Significant unobservable inputs (Level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable | 85,500 | 82,500
Recurring basis | Net Sales Milestones and Royalties |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable | 80,900 | 81,500
Recurring basis | Net Sales Milestones and Royalties | Significant unobservable inputs (Level 3) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Contingent consideration payable | 80,900 | 81,500
Recurring basis | Marketable securities |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities - available for sale | 10,249 | 22,610
Marketable securities - equity investments | 108,559 | 108,261
Recurring basis | Marketable securities | Quoted prices in active markets for identical assets (Level 1) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities - equity investments | 108,559 | 108,261
Recurring basis | Marketable securities | Significant other observable inputs (Level 2) |  |
Financial assets and liabilities measured at fair value on recurring basis |  |
Marketable securities - available for sale | $ 10,249 | $ 22,610

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