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Debt - (Tables)

3 Months Ended

Mar. 31, 2023

Debt Instrument, Redemption [Line Items]

Summary of liability for sale of future royalties

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​	​	​	​	​
​		Three Months Ended March 31,		​
Liability for sale of future royalties- (current and noncurrent)	​	2023		​
Beginning balance as of December 31, 2022	​	$	757,886	​
Less: Non-cash royalty revenue payable to RPI	​	​	(13,237)	​
Plus: Non-cash interest expense recognized	​	​	18,902	​
Ending balance	​	$	763,551	​
Effective interest rate as of March 31, 2023	​		9.8	%

​

1.50% Convertible senior notes due 2026

Debt Instrument, Redemption [Line Items]

Summary of convertible notes

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​	​	​	​	​	​	​	​
​		​	​	​	​	​	​
​	​	March 31, 2023		​	December 31, 2022		​
Principal	​	$	287,500	​	$	287,500	​
Less: Debt issuance costs	​		(4,168)	​		(4,456)	​
Net carrying amount	​	$	283,332	​	$	283,044	​

Summary of interest expense recognized related to the Convertible Notes

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​	​	​	​	​	​	​	​
​		​	​	​	​	​
​	​	Three Months Ended March 31,					​
​	​	2023		​	2022		​
Contractual interest expense	​	$	1,069	​	$	1,069	​
Amortization of debt issuance costs	​	​	288	​	​	283	​
Total	​	$	1,357	​	$	1,352	​
Effective interest rate	​	​	1.9	%	​	1.9	%

​

3.00% Convertible senior notes due 2022

Debt Instrument, Redemption [Line Items]

Summary of interest expense recognized related to the Convertible Notes

​

​	​	​	​	​	​	​	​
​	​	​	​	​	​		​
​	Three Months Ended March 31,						​
​	2023			2022			​
Contractual interest expense	$	—	​	$	1,110	​	​
Amortization of debt issuance costs		—	​		181	​	​
Total	$	—	​	$	1,291	​	​
Effective interest rate		—	%		3.5	%	​

Senior Secured Term Loan Facility

Debt Instrument, Redemption [Line Items]

Summary of interest expense recognized related to debt

​

​	​	​	​
​	Three Months Ended		​
​	March 31,		​
​	2023		​
Contractual interest expense	$	9,178	​
Amortization of debt issuance costs		150	​
Total	$	9,328	​
Effective interest rate	​	13.2	%

​

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