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Revenue recognition - Net Product Sales (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2023 USD ($) segment Distributor country	Mar. 31, 2022 USD ($) country segment Distributor
Revenue recognition
Number of operating segments | segment	1	1
Revenue	$ 220,382	$ 148,735
Net product revenue | Geographic concentration risk
Revenue recognition
Number of countries exceeding 10% of net product sales | country	3	2
Percentage of net product sales threshold	10.00%	10.00%
Net product revenue | Geographic concentration risk | United States
Revenue recognition
Revenue	$ 54,600	$ 48,600
Net product revenue | Geographic concentration risk | Russia
Revenue recognition
Revenue	44,600
Net product revenue | Geographic concentration risk | Brazil
Revenue recognition
Revenue	$ 25,900	$ 25,800
Net product revenue | Customer concentration risk
Revenue recognition
Number of distributors | Distributor	2	2
Net product revenue | Customer concentration risk | Minimum
Revenue recognition
Percentage of net product sales threshold	10.00%	10.00%
Net product revenue
Revenue recognition
Revenue	$ 187,557	$ 129,832
Net product revenue | Non-US
Revenue recognition
Revenue	133,000	81,200
Emflaza | United States
Revenue recognition
Revenue	54,600	48,600
Translarna | Non-US
Revenue recognition
Revenue	$ 115,100	$ 79,200

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