XML 80 R68.htm IDEA: XBRL DOCUMENT v3.23.1
Intangible assets and goodwill - Definite-lived Intangibles (Details) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Definite-lived intangible assets      
Milestone Payable $ 32,500    
Accrued royalties 32,694   $ 40,546
Definite-lived intangibles      
Amortization (39,415) $ (23,473)  
Finite-Lived Intangible Assets, Net $ 232,639    
Weighted Average      
Definite-lived intangible assets      
Remaining amortization period 5 years    
Emflaza asset acquisition      
Definite-lived intangible assets      
Milestone obligation payments recorded $ 17,500 62,100  
Emflaza asset acquisition | Accounts payable and accrued expenses      
Definite-lived intangible assets      
Milestone Payable 17,500    
Emflaza asset acquisition | Sales Milestones      
Definite-lived intangible assets      
Milestone obligation payments recorded   50,000  
Akcea | Waylivra      
Definite-lived intangible assets      
Royalty payments 0    
Akcea | Tegsedi      
Definite-lived intangible assets      
Royalty payments 2,000 $ 400  
Akcea | Tegsedi | Accounts payable and accrued expenses      
Definite-lived intangible assets      
Accrued royalties 2,000    
Definite-lived intangible assets      
Definite-lived intangibles      
Beginning balance - Definite-lived assets, Gross 526,228    
Additions 19,516    
Foreign Currency Translation 301    
Ending balance - Definite-lived assets, Gross 546,045    
Beginning balance - Accumulated amortization (273,903)    
Amortization (39,415)    
Foreign Currency Translation - Accumulated amortization (88)    
Ending balance - Accumulated amortization (313,406)    
Finite-Lived Intangible Assets, Net 232,639    
Definite-lived intangible assets | Emflaza      
Definite-lived intangibles      
Beginning balance - Definite-lived assets, Gross 420,253    
Additions 17,515    
Ending balance - Definite-lived assets, Gross 437,768    
Beginning balance - Accumulated amortization (266,023)    
Amortization (36,996)    
Ending balance - Accumulated amortization (303,019)    
Definite-lived intangible assets | Waylivra      
Definite-lived intangibles      
Beginning balance - Definite-lived assets, Gross 9,316    
Foreign Currency Translation 170    
Ending balance - Definite-lived assets, Gross 9,486    
Beginning balance - Accumulated amortization (2,751)    
Amortization (261)    
Foreign Currency Translation - Accumulated amortization (52)    
Ending balance - Accumulated amortization (3,064)    
Definite-lived intangible assets | Tegsedi      
Definite-lived intangibles      
Beginning balance - Definite-lived assets, Gross 7,109    
Additions 2,001    
Foreign Currency Translation 131    
Ending balance - Definite-lived assets, Gross 9,241    
Beginning balance - Accumulated amortization (1,709)    
Amortization (292)    
Foreign Currency Translation - Accumulated amortization (36)    
Ending balance - Accumulated amortization (2,037)    
Definite-lived intangible assets | Upstaza      
Definite-lived intangibles      
Beginning balance - Definite-lived assets, Gross 89,550    
Ending balance - Definite-lived assets, Gross 89,550    
Beginning balance - Accumulated amortization (3,420)    
Amortization (1,866)    
Ending balance - Accumulated amortization $ (5,286)