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Accounts payable and accrued expenses - Narrative (Details) - USD ($) $ in Thousands | Jun. 30, 2023 | Dec. 31, 2022
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Payables and Accruals [Abstract] |  |
Employee compensation, benefits, and related accruals | $ 48,707 | $ 62,669
Income tax payable | 11,149 | 4,712
Consulting and contracted research | 28,522 | 38,882
Professional fees | 3,750 | 3,093
Sales allowance | 71,979 | 63,787
Sales rebates | 108,376 | 67,355
Royalties | 51,720 | 40,546
Accounts payable | 25,741 | 27,268
Other | 8,618 | 12,054
Accounts payable and accrued expenses | $ 358,562 | $ 320,366

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