XML 37 R26.htm IDEA: XBRL DOCUMENT
v3.23.2

Stock award plan - (Tables) | 6 Months Ended
--- | ---
Jun. 30, 2023
Share-based Payment Arrangement [Abstract] |
Summary of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | Weighted- |  |  | ​ | ​
​ | ​ | ​ | ​ | Weighted- | ​ | average | ​ | ​ | Aggregate
​ | ​ | ​ | ​ | average | ​ | remaining | ​ | ​ | intrinsic
​ | ​ | Number of | ​ | exercise | ​ | contractual | ​ | ​ | value(in
​ | ​ | options | ​ | price | ​ | term | ​ | ​ | thousands)
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​
Outstanding at December 31, 2022 |  | 11,502,417 | ​ | $ | 43.33 |  |  |  | ​ | ​ |
Granted |  | 992,674 | ​ | $ | 41.39 |  |  |  | ​ | ​ |
Exercised |  | (692,612) | ​ | $ | 29.37 |  |  |  | ​ | ​ |
Forfeited/Cancelled |  | (127,988) | ​ | $ | 49.84 |  |  |  | ​ | ​ |
Outstanding at June 30, 2023 |  | 11,674,491 | ​ | $ | 43.92 |  | 6.27 | years | ​ | $ | 44,184
Vested or Expected to vest at June 30, 2023 |  | 3,112,415 | ​ | $ | 47.05 |  | 8.34 | years | ​ | $ | 3,578
Exercisable at June 30, 2023 |  | 8,259,224 | ​ | $ | 42.71 |  | 5.40 | years | ​ | $ | 40,195
​
Schedule of assumptions used to estimate fair values of grants made on the date of grant | ​
​ | ​ | ​
​ |  | Six months ended
​ |  | June 30, 2023
Risk-free interest rate |  | 3.54% - 3.88%
Expected volatility |  | 53% - 54%
Expected term |  | 5.5 years
Summary of information on the Company's restricted stock | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Restricted Stock Awards and Units
​ | ​ | ​ | ​ | Weighted
​ | ​ | ​ | ​ | Average
​ | ​ | ​ | ​ | Grant
​ | ​ | Number of | ​ | Date
​ |  | Shares |  | Fair Value
Unvested at December 31, 2022 | ​ | 2,516,336 | ​ | $ | 45.67
Granted |  | 1,943,288 | ​ | ​ | 40.00
Vested |  | (751,448) | ​ | ​ | 46.46
Forfeited |  | (91,237) | ​ | ​ | 42.49
Unvested at June 30, 2023 |  | 3,616,939 | ​ | $ | 42.54
Schedule of share-based compensation expense recorded in the statement of operations | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended June 30, | ​ | Six Months Ended June 30, | ​
​ |  | 2023 |  | 2022 |  | 2023 |  | 2022 | ​
Research and development | ​ | $ | 15,529 | ​ | $ | 13,798 | ​ | $ | 30,842 | ​ | $ | 26,832 | ​
Selling, general and administrative | ​ |  | 13,842 | ​ |  | 13,932 | ​ |  | 27,344 | ​ |  | 27,487 | ​
Total | ​ | $ | 29,371 | ​ | $ | 27,730 | ​ | $ | 58,186 | ​ | $ | 54,319 | ​
​

X
- References No definition available. + Details
Name: | us-gaap_DisclosureOfCompensationRelatedCostsSharebasedPaymentsAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of the changes in outstanding nonvested restricted stock shares. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Subparagraph (c) -Paragraph 2 -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
Name: | us-gaap_NonvestedRestrictedStockSharesActivityTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
Name: | us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
Name: | us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
Name: | us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration