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Accounts payable and accrued expenses | 6 Months Ended
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Jun. 30, 2023
Payables and Accruals [Abstract] |
Accounts payable and accrued expenses | 5. Accounts payable and accrued expenses Accounts payable and accrued expenses at June 30, 2023 and December 31, 2022 consist of the following: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | June 30, | ​ | December 31, | ​
​ |  | 2023 |  | 2022 | ​
Employee compensation, benefits, and related accruals | ​ | $ | 48,707 | ​ | $ | 62,669 | ​
Income tax payable | ​ | ​ | 11,149 | ​ | ​ | 4,712 | ​
Consulting and contracted research | ​ |  | 28,522 | ​ |  | 38,882 | ​
Professional fees | ​ |  | 3,750 | ​ |  | 3,093 | ​
Sales allowance | ​ |  | 71,979 | ​ |  | 63,787 | ​
Sales rebates | ​ |  | 108,376 | ​ |  | 67,355 | ​
Royalties | ​ | ​ | 51,720 | ​ | ​ | 40,546 | ​
Accounts payable | ​ |  | 25,741 | ​ |  | 27,268 | ​
Other | ​ |  | 8,618 | ​ |  | 12,054 | ​
Total | ​ | $ | 358,562 | ​ | $ | 320,366 | ​
​ During the three and six month periods ended June 30, 2023, the Company incurred $8.0 million of restructuring costs from a reduction in workforce in connection with the Company’s strategic pipeline prioritization and discontinuation of its preclinical and early research programs in its gene therapy platform. The costs are included in research and development and selling, general, and administrative expenses on the Company’s consolidated statement of operations. As of June 30, 2023, the remaining $6.0 million of accrued restructuring costs are included above within employee compensation, benefits, and related accruals.

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- Definition The entire disclosure for accounts payable, accrued expenses, and other liabilities that are classified as current at the end of the reporting period. + References No definition available. + Details
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