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Intangible assets and goodwill - (Tables)
6 Months Ended
Jun. 30, 2023
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of definite lived intangible assets

Definite-lived intangible assets consisted of the following at June 30, 2023 and December 31, 2022:

Ending Balance at

Reclass from

Foreign

Ending Balance at

Definite-lived

December 31,

Indefinite Lived to

currency

June 30,

intangibles assets, gross

    

2022

    

Additions

    

Definite Lived

    

Impairment

    

translation

    

2023

Emflaza

$

420,253

$

46,538

$

$

$

$

466,791

Waylivra

9,316

252

9,568

Tegsedi

7,109

3,488

210

10,807

Upstaza

89,550

89,550

Total definite-lived intangibles, gross

$

526,228

$

50,026

$

$

$

462

$

576,716

Ending Balance at

Foreign

Ending Balance at

Definite-lived

December 31,

currency

June 30,

intangibles assets, accumulated amortization

    

2022

    

Amortization

    

translation

    

2023

Emflaza

$

(266,023)

$

(81,908)

$

$

(347,931)

Waylivra

(2,751)

(524)

(81)

(3,356)

Tegsedi

(1,709)

(649)

(57)

(2,415)

Upstaza

(3,420)

(3,731)

(7,151)

Total definite-lived intangibles, accumulated amortization

$

(273,903)

$

(86,812)

$

(138)

$

(360,853)

Total definite-lived intangibles, net

$

215,863

Schedule of estimated future amortization of intangible assets

    

As of June 30, 2023

2023

$

94,806

2024

 

39,003

2025

 

9,966

2026

 

9,966

2027 and thereafter

 

62,122

Total

$

215,863

Schedule of indefinite lived intangible assets

Indefinite-lived intangible assets consisted of the following at June 30, 2023 and December 31, 2022:

Ending Balance at

Reclass from

Foreign

Ending Balance at

Indefinite-lived

December 31,

Indefinite Lived to

currency

June 30,

intangibles assets

    

2022

    

Additions

    

Definite Lived

    

Impairment

    

translation

    

2023

Upstaza

$

235,766

$

$

$

$

$

235,766

PTC-FA

112,500

(112,500)

PTC-AS

105,300

(105,300)

Total indefinite-lived intangibles

$

453,566

$

$

$

(217,800)

$

$

235,766

Total intangible assets, net

$

451,629