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Summary of significant accounting policies - Collaboration and Royalty Revenue (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Collaboration and royalty revenue
Revenue	$ 213,808	$ 165,526	$ 434,190	$ 314,262
Collaboration and grant revenue
Collaboration and royalty revenue
Revenue			6	7
Royalty revenue
Collaboration and royalty revenue
Revenue	36,853	21,825	67,684	40,721
SMA License Agreement | Collaboration and grant revenue
Collaboration and royalty revenue
Revenue	0	0
SMA License Agreement | Royalty revenue
Collaboration and royalty revenue
Revenue	$ 36,900	$ 21,800	$ 67,700	$ 40,700

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