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v3.23.3

Summary of significant accounting policies - Narrative (Details) $ in Thousands |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | ---
Dec. 22, 2017 | May 31, 2023 USD ($) | Jun. 30, 2022 USD ($) | Jul. 31, 2020 USD ($) | Sep. 30, 2023 USD ($) country segment | Sep. 30, 2022 USD ($) segment country | Sep. 30, 2023 USD ($) country segment | Sep. 30, 2022 USD ($) segment country | Dec. 31, 2019 USD ($) | Mar. 31, 2023 USD ($) | Dec. 31, 2022 USD ($) | Dec. 31, 2018 USD ($)
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Number of operating segments | segment |  |  |  |  | 1 | 1 | 1 | 1 |  |  |  |
Allowance for credit loss |  |  |  |  | $ 0 | $ 0 | $ 0 | $ 0 |  |  |  |
Increase in allowance for credit losses |  |  |  |  | 0 | 0 | 0 | 0 |  |  |  |
Allowance for doubtful accounts receivable |  |  |  |  | 1,000 |  | 1,000 |  |  |  | $ 300 |
Bad debt expense |  |  |  |  | 400 |  | 700 |  |  |  |  |
Revenue |  |  |  |  | 196,576 | $ 217,127 | 630,766 | $ 531,389 |  |  |  |
Cash consideration received from Royalty Purchase Agreement |  |  |  | $ 650,000 |  |  |  |  |  |  |  |
Income taxes |  |  |  |  |  |  |  |  |  |  |  |
Federal income tax statutory rate | 21.00% |  |  |  |  |  |  |  |  |  |  |
Deferred tax benefit |  | $ 50,900 |  |  |  |  | 50,909 |  |  |  |  |
Impairment of indefinite-lived intangibles excluding goodwill |  |  |  |  |  |  | 217,800 |  |  |  |  |
PTC-FA and PTC-AS |  |  |  |  |  |  |  |  |  |  |  |
Income taxes |  |  |  |  |  |  |  |  |  |  |  |
Impairment of indefinite-lived intangibles excluding goodwill |  |  |  |  |  |  | 217,800 |  |  |  |  |
Indefinite-lived intangible assets |  |  |  |  |  |  |  |  |  |  |  |
Income taxes |  |  |  |  |  |  |  |  |  |  |  |
Impairment of indefinite-lived intangibles excluding goodwill |  |  |  |  |  |  | 217,800 |  |  |  |  |
Indefinite-lived intangible assets | PTC-FA and PTC-AS |  |  |  |  |  |  |  |  |  |  |  |
Income taxes |  |  |  |  |  |  |  |  |  |  |  |
Impairment of indefinite-lived intangibles excluding goodwill |  |  |  |  |  |  | 217,800 |  |  |  |  |
Agilis |  |  |  |  |  |  |  |  |  |  |  |
Income taxes |  |  |  |  |  |  |  |  |  |  |  |
Deferred tax liability |  |  |  |  |  |  |  |  |  |  |  | $ 122,000
Deposits and other assets |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Bank guarantee |  |  |  |  | $ 600 |  | $ 600 |  |  |  |  |
Blackstone Credit Agreement |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Credit agreement reserve |  |  |  |  |  |  |  |  |  | $ 50,000 |  |
Hopewell Campus |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Period after which letter of credit may be reduced if lease is not in default |  |  |  |  |  |  |  |  | 5 years |  |  |
Hopewell Campus | Minimum |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Term for letter of credit (in years) |  |  |  |  |  |  |  |  | 5 years |  |  |
Hopewell Campus | Deposits and other assets |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Letters of credit |  |  |  |  |  |  |  |  | $ 7,500 |  |  |
Hopewell Campus | Fifth Anniversary |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Letters of credit |  |  |  |  |  |  |  |  | $ 3,800 |  |  |
Warren Premises |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Period after which letter of credit may be reduced if lease is not in default |  |  | 5 years |  |  |  |  |  |  |  |  |
Warren Premises | Deposits and other assets |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Letters of credit |  |  | $ 8,100 |  |  |  |  |  |  |  |  |
Warren Premises | Fifth Anniversary |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Letters of credit |  |  | $ 4,100 |  |  |  |  |  |  |  |  |
Net product revenue | United States |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Number of countries exceeding 10% of net product sales | country |  |  |  |  | 1 |  |  |  |  |  |  |
Net product revenue | Geographic concentration risk |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Number of countries exceeding 10% of net product sales | country |  |  |  |  | 1 | 2 | 3 | 2 |  |  |  |
Percentage of net product sales threshold |  |  |  |  | 10.00% | 10.00% | 10.00% | 10.00% |  |  |  |
Net product revenue | Geographic concentration risk | Russia |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | $ 28,300 | $ 69,000 | $ 57,100 |  |  |  |
Net product revenue | Geographic concentration risk | Brazil |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  | 52,500 |  |  |  |  |
Net product revenue | Geographic concentration risk | United States |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  | $ 67,400 | 54,800 | 187,700 | 160,100 |  |  |  |
Net product revenue |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  | 144,038 | 134,186 | 506,187 | 407,720 |  |  |  |
Net product revenue | Non-US |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  | 76,600 | 79,400 | 318,500 | 247,600 |  |  |  |
Emflaza | United States |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  | 67,400 | 54,800 | 187,700 | 160,100 |  |  |  |
Translarna | Non-US |  |  |  |  |  |  |  |  |  |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  | $ 69,000 | $ 76,600 | $ 280,600 | $ 232,900 |  |  |  |

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