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Stock award plan - (Tables) | 9 Months Ended
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Sep. 30, 2023
Share-based Payment Arrangement [Abstract] |
Summary of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | Weighted- |  |  | ​ | ​
​ | ​ | ​ | ​ | Weighted- | ​ | average | ​ | ​ | Aggregate
​ | ​ | ​ | ​ | average | ​ | remaining | ​ | ​ | intrinsic
​ | ​ | Number of | ​ | exercise | ​ | contractual | ​ | ​ | value(in
​ | ​ | options | ​ | price | ​ | term | ​ | ​ | thousands)
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​
Outstanding at December 31, 2022 |  | 11,502,417 | ​ | $ | 43.33 |  |  |  | ​ | ​ |
Granted |  | 1,059,054 | ​ | $ | 41.29 |  |  |  | ​ | ​ |
Exercised |  | (806,407) | ​ | $ | 29.48 |  |  |  | ​ | ​ |
Forfeited/Cancelled |  | (318,281) | ​ | $ | 47.84 |  |  |  | ​ | ​ |
Outstanding at September 30, 2023 |  | 11,436,783 | ​ | $ | 43.99 |  | 5.87 | years | ​ | $ | 5,084
Vested or Expected to vest at September 30, 2023 |  | 2,357,250 | ​ | $ | 46.72 |  | 8.23 | years | ​ | $ | —
Exercisable at September 30, 2023 |  | 8,533,144 | ​ | $ | 43.18 |  | 5.05 | years | ​ | $ | 5,084
​
Schedule of assumptions used to estimate fair values of grants made on the date of grant | ​
​ | ​ | ​
​ |  | Nine months ended
​ |  | September 30, 2023
Risk-free interest rate |  | 3.54% - 3.91%
Expected volatility |  | 53% - 54%
Expected term |  | 5.5 years
Summary of information on the Company's restricted stock | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Restricted Stock Awards and Units
​ | ​ | ​ | ​ | Weighted
​ | ​ | ​ | ​ | Average
​ | ​ | ​ | ​ | Grant
​ | ​ | Number of | ​ | Date
​ |  | Shares |  | Fair Value
Unvested at December 31, 2022 | ​ | 2,516,336 | ​ | $ | 45.67
Granted |  | 1,973,973 | ​ | ​ | 40.00
Vested |  | (778,442) | ​ | ​ | 46.34
Forfeited |  | (297,765) | ​ | ​ | 42.65
Unvested at September 30, 2023 |  | 3,414,102 | ​ | $ | 42.50
Schedule of share-based compensation expense recorded in the statement of operations | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended September 30, | ​ | Nine Months Ended September 30, | ​
​ |  | 2023 |  | 2022 |  | 2023 |  | 2022 | ​
Research and development | ​ | $ | 13,986 | ​ | $ | 15,063 | ​ | $ | 44,828 | ​ | $ | 41,896 | ​
Selling, general and administrative | ​ |  | 12,956 | ​ |  | 13,607 | ​ |  | 40,300 | ​ |  | 41,093 | ​
Total | ​ | $ | 26,942 | ​ | $ | 28,670 | ​ | $ | 85,128 | ​ | $ | 82,989 | ​
​

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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