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Intangible assets and goodwill - (Tables)
9 Months Ended
Sep. 30, 2023
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of definite lived intangible assets

Definite-lived intangible assets consisted of the following at September 30, 2023 and December 31, 2022:

Ending Balance at

Reclass from

Foreign

Ending Balance at

Definite-lived

December 31,

Indefinite Lived to

currency

September 30,

intangibles assets, gross

    

2022

    

Additions

    

Definite Lived

    

Impairment

    

translation

    

2023

Emflaza

$

420,253

$

76,454

$

$

$

$

496,707

Waylivra

9,316

157

(96)

9,377

Tegsedi

7,109

4,299

(183)

11,225

Upstaza

89,550

89,550

Total definite-lived intangibles, gross

$

526,228

$

80,910

$

$

$

(279)

$

606,859

Ending Balance at

Foreign

Ending Balance at

Definite-lived

December 31,

currency

September 30,

intangibles assets, accumulated amortization

    

2022

    

Amortization

    

translation

    

2023

Emflaza

$

(266,023)

$

(138,038)

$

$

(404,061)

Waylivra

(2,751)

(791)

45

(3,497)

Tegsedi

(1,709)

(1,035)

36

(2,708)

Upstaza

(3,420)

(5,597)

(9,017)

Total definite-lived intangibles, accumulated amortization

$

(273,903)

$

(145,461)

$

81

$

(419,283)

Total definite-lived intangibles, net

$

187,576

Schedule of estimated future amortization of intangible assets

    

As of September 30, 2023

2023

$

58,640

2024

 

46,557

2025

 

10,041

2026

 

10,041

2027 and thereafter

 

62,297

Total

$

187,576

Schedule of indefinite lived intangible assets

Indefinite-lived intangible assets consisted of the following at September 30, 2023 and December 31, 2022:

Ending Balance at

Reclass from

Foreign

Ending Balance at

Indefinite-lived

December 31,

Indefinite Lived to

currency

September 30,

intangibles assets

    

2022

    

Additions

    

Definite Lived

    

Impairment

    

translation

    

2023

Upstaza

$

235,766

$

$

$

$

$

235,766

PTC-FA

112,500

(112,500)

PTC-AS

105,300

(105,300)

Total indefinite-lived intangibles

$

453,566

$

$

$

(217,800)

$

$

235,766

Total intangible assets, net

$

423,342