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Leases - Narrative (Details)
$ in Thousands
 1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jul. 01, 2020
USD ($)
ft²
item
May 31, 2022
USD ($)
ft²
building
period
Sep. 30, 2023
USD ($)
lease
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
lease
Sep. 30, 2022
USD ($)
Dec. 31, 2020
USD ($)
Dec. 31, 2022
USD ($)
Jun. 19, 2020
USD ($)
Leases                  
Number of operating leases | lease     2   2        
Operating lease, expense     $ 7,100 $ 6,800 $ 21,500 $ 18,000      
Finance Lease, Liability     19,795   19,795        
Finance lease liabilities- current     2,611   2,611     $ 3,000  
Finance lease liabilities- noncurrent     17,184   17,184     18,675  
Aggregate rent, Initial term     257,664   257,664        
Operating lease ROU assets     94,072   94,072     102,430  
Operating Lease, Liability     111,385   111,385        
Research and development     164,212 165,462 545,210 462,802      
MassBio                  
Leases                  
Finance lease cost     400 $ 400 1,100 $ 1,200      
Finance Lease, Liability                 $ 41,400
Finance lease liabilities- current     2,600   2,600     3,000  
Finance lease liabilities- noncurrent     $ 17,200   $ 17,200     $ 18,700  
Finance lease ROU asset                 $ 41,400
Finance lease, term of contract                 12 years 6 months
Research and development             $ 41,400    
Minimum                  
Leases                  
Operating lease, term of contract     4 months 24 days   4 months 24 days        
Maximum                  
Leases                  
Operating lease, term of contract     15 years 8 months 12 days   15 years 8 months 12 days        
Renewal term     20 years   20 years        
Hopewell Campus                  
Leases                  
Operating lease, term of contract 15 years                
Area of real estate property | ft² 220,500                
Renewal term 10 years                
Number of renewable terms | item 2                
Lessee, Operating Lease, Existence of Option to Extend [true false] true                
Aggregate rent, Initial term $ 111,500                
Percent of market rate 95.00%                
Warren Premises                  
Leases                  
Operating lease, term of contract   17 years              
Number of buildings leased | building   2              
Area of real estate property | ft²   360,000              
Renewal term   5 years              
Number of renewable terms | period   3              
Lessee, Operating Lease, Existence of Option to Extend [true false]   true              
Aggregate rent, Initial term   $ 163,000              
Operating lease ROU assets   28,900              
Operating Lease, Liability   $ 28,900              
Base rent abatement period   3 years              
Base rent abatement   $ 18,600              
Aggregate rent net of base rate abatement, initial term   144,400              
Allowance for lease improvements   36,200              
Commitment to fund construction account   3,600              
Payment due from lessor at issuance of temporary certificate of occupancy   $ 5,000