<SEC-DOCUMENT>0001415889-23-005991.txt : 20230404
<SEC-HEADER>0001415889-23-005991.hdr.sgml : 20230404
<ACCEPTANCE-DATETIME>20230404160703
ACCESSION NUMBER:		0001415889-23-005991
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20230331
FILED AS OF DATE:		20230404
DATE AS OF CHANGE:		20230404

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SOUTHWELL DAVID P
		CENTRAL INDEX KEY:			0001251553

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35969
		FILM NUMBER:		23797362

	MAIL ADDRESS:	
		STREET 1:		C/O INOTEK PHARMACEUTICALS CORPORATION
		STREET 2:		91 HARTWELL AVENUE
		CITY:			LEXINGTON
		STATE:			MA
		ZIP:			02421

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PTC THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001070081
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				043416587
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		100 CORPORATE COURT
		CITY:			SOUTH PLAINFIELD
		STATE:			NJ
		ZIP:			07080-2449
		BUSINESS PHONE:		9082227000

	MAIL ADDRESS:	
		STREET 1:		100 CORPORATE COURT
		CITY:			SOUTH PLAINFIELD
		STATE:			NJ
		ZIP:			07080-2449

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PTC THERAPEUTICS INC
		DATE OF NAME CHANGE:	19980909
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
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<TEXT>
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    <schemaVersion>X0407</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2023-03-31</periodOfReport>

    <issuer>
        <issuerCik>0001070081</issuerCik>
        <issuerName>PTC THERAPEUTICS, INC.</issuerName>
        <issuerTradingSymbol>PTCT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
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            <rptOwnerCik>0001251553</rptOwnerCik>
            <rptOwnerName>SOUTHWELL DAVID P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O PTC THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>100 CORPORATE COURT</rptOwnerStreet2>
            <rptOwnerCity>SOUTH PLAINFIELD</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>07080</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>true</isDirector>
            <isOfficer>false</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle></officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

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            </securityTitle>
            <transactionDate>
                <value>2023-03-31</value>
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                <transactionShares>
                    <value>2571</value>
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                <transactionPricePerShare>
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                <transactionAcquiredDisposedCode>
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        </nonDerivativeTransaction>
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    <derivativeTable>
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            <securityTitle>
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            </securityTitle>
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            <expirationDate>
                <value>2028-01-02</value>
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                <footnoteId id="F3"/>
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            <expirationDate>
                <value>2025-01-02</value>
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                <underlyingSecurityShares>
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                <sharesOwnedFollowingTransaction>
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        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>30.86</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F3"/>
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            <expirationDate>
                <value>2026-01-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
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                <sharesOwnedFollowingTransaction>
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            <securityTitle>
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            </securityTitle>
            <conversionOrExercisePrice>
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            <expirationDate>
                <value>2029-01-02</value>
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                <underlyingSecurityShares>
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            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
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                </sharesOwnedFollowingTransaction>
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            <securityTitle>
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            <conversionOrExercisePrice>
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            <exerciseDate>
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            <expirationDate>
                <value>2030-01-28</value>
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            <underlyingSecurity>
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                <sharesOwnedFollowingTransaction>
                    <value>10000</value>
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            <securityTitle>
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                <value>2031-01-05</value>
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        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
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            <conversionOrExercisePrice>
                <value>39.42</value>
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            <exerciseDate>
                <footnoteId id="F4"/>
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            <expirationDate>
                <value>2033-01-04</value>
            </expirationDate>
            <underlyingSecurity>
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        </derivativeHolding>
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    <footnotes>
        <footnote id="F1">This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on February 24, 2023.</footnote>
        <footnote id="F2">This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $50.00 to $50.17 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price.</footnote>
        <footnote id="F3">Currently exercisable.</footnote>
        <footnote id="F4">This option was granted on January 5, 2023 and vests over one year in twelve equal monthly installments, commencing on February 5, 2023.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Avraham S. Adler, Attorney-in-Fact</signatureName>
        <signatureDate>2023-04-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
