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Summary of significant accounting policies - Liability for Sale of Future Royalties (Details) $ in Thousands |  |  | 12 Months Ended
--- | --- | --- | ---
Oct. 18, 2023 USD ($) Option | Jul. 17, 2020 USD ($) | Dec. 31, 2023 USD ($)
Assigned royalty payments |  |  |
Cash consideration received from Royalty Purchase Agreement |  |  | $ 1,000,000
Assigned royalty payment, retained percentage |  | 57.067% |
Remaining potential milestones that can be achieved |  |  | $ 150,000
Effective interest rate of the liability component |  |  | 10.80%
Loss on extinguishment of debt |  |  | $ 137,558
Aggregate Royalty Purchase Agreements | Royalty Pharma |  |  |
Assigned royalty payments |  |  |
Total percentage of royalty rights assigned | 80.9777% |  |
Original Royalty Purchase Agreement |  |  |
Assigned royalty payments |  |  |
Assigned royalty payment, percentage |  | 42.933% |
Cash consideration received from Royalty Purchase Agreement |  | $ 650,000 |
Royalty purchase agreement termination period once there are no further royalty payment obligations |  | 60 days |
Royalty purchase agreement, payment maximum | $ 1,300,000 | $ 1,300,000 |
Original Royalty Purchase Agreement | Royalty Pharma |  |  |
Assigned royalty payments |  |  |
Royalty purchase agreement, payment maximum | 1,300,000 |  |
A&R Royalty Purchase Agreement |  |  |
Assigned royalty payments |  |  |
Cash consideration received from Royalty Purchase Agreement | $ 1,000,000 |  |
Royalty purchase agreement termination period once there are no further royalty payment obligations | 60 days |  |
Effective interest rate of the liability component | 10.80% |  |
Retained Royalty Rights percentage sold | 38.0447% |  |
Percentage of total royalty payable after threshold royalties received | 66.6667% |  |
Additional cash consideration | $ 500,000 |  |
Number of put options held by the company | Option | 5 |  |
Maximum number of put options which can be exercised before Royalty Pharma can exercise a call option | Option | 2 |  |
Maximum percentage of remaining retained royalty rights that are available upon exercise of call option | 50.00% |  |
Fair value of liability for sale of future royalties. | $ 1,809,900 |  |
Loss on extinguishment of debt | $ 44,900 |  |
A&R Royalty Purchase Agreement | Royalty Pharma |  |  |
Assigned royalty payments |  |  |
Percentage of maximum royalty payable until assigned royalty rights | 90.4888% |  |
Percentage of maximum royalty payable thereafter assigned royalty rights | 83.3333% |  |

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