XML 86 R71.htm IDEA: XBRL DOCUMENT v3.24.0.1
Stock award plan - Narrative (Details) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
Jun. 08, 2022
Dec. 31, 2022
Dec. 31, 2020
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Apr. 30, 2022
Jun. 30, 2021
May 31, 2021
Jan. 31, 2020
Stock option plan                    
Share-based compensation expense       $ 101,636 $ 110,333 $ 103,513        
Unrecognized compensation cost       $ 119,600            
Weighted average remaining service period for recognition of unrecognized compensation cost       2 years 1 month 6 days            
Stock option                    
Stock option plan                    
Granted (in shares)       1,117,284 1,685,435 2,487,234        
Options forfeited (in shares)       2,196,820 458,737 742,458        
Expected dividend yield (as a percent)       0.00% 0.00% 0.00%        
Weighted average grant date fair value (in dollars per share)       $ 21.27 $ 23.54 $ 43.05        
Stock option | Maximum                    
Stock option plan                    
Vesting period       4 years            
Employee Stock Purchase Plan                    
Stock option plan                    
Number of shares authorized (in shares)               2,000,000 1,000,000  
Award requisite service period       6 months            
Share-based compensation expense       $ 2,400            
Employee Stock Purchase Plan | Minimum                    
Stock option plan                    
Purchase price of common stock, percent       85.00%            
Employee stock purchase plan, voting percentage limit       5.00%            
1998 Employee, Director, and Consultant Stock Option Plan, 2009 Equity and Long-term Incentive Plan, and 2013 Stock Incentive Plan                    
Stock option plan                    
Number of shares available for issuance       0            
Amended 2013 LTIP                    
Stock option plan                    
Number of additional shares authorized (in shares) 8,475,000                  
Amended 2013 LTIP | Maximum                    
Stock option plan                    
Number of shares authorized (in shares) 16,724,212                  
2013 Long Term Incentive Plan                    
Stock option plan                    
Number of shares available for issuance       8,680,209            
2020 Inducement Stock Incentive Plan                    
Stock option plan                    
Number of shares available for issuance       1,834,322            
Number of additional shares authorized (in shares)     1,000,000              
2020 Inducement Stock Incentive Plan | Maximum                    
Stock option plan                    
Number of shares authorized (in shares)                   1,000,000
2020 Inducement Stock Incentive Plan | Common stock | Maximum                    
Stock option plan                    
Number of shares authorized (in shares)             1,300,000      
Number of additional shares authorized (in shares)   1,700,000                
2020 Inducement Stock Incentive Plan | Stock option                    
Stock option plan                    
Granted (in shares)       139,040            
Stockholder's specified ownership percentage       10.00%            
Expiration period       10 years            
Granted (in dollars per share)       $ 41.25            
Options forfeited (in shares)       270,583            
2020 Inducement Stock Incentive Plan | Stock option | Minimum                    
Stock option plan                    
Stock options granted, exercise price as percentage of the fair market value of common stock at grant date       100.00%            
Stock options granted to stockholder with specified ownership percentage, exercise price as percentage of the fair market value of common stock at grant date       110.00%            
2020 Inducement Stock Incentive Plan | Restricted stock units                    
Stock option plan                    
Granted (in shares)       105,370            
Units forfeited (in shares)       79,195