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Revenue recognition - Net Product Sales (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2023 USD ($) country Distributor	Dec. 31, 2022 USD ($) country Distributor	Dec. 31, 2021 USD ($) country Distributor
Revenue recognition
Revenue	$ 937,822	$ 698,801	$ 538,593
United States
Revenue recognition
Revenue	531,661	381,862
Non-US
Revenue recognition
Revenue	406,161	316,939
Net product revenue
Revenue recognition
Contract with Customer, Liability	$ 0	$ 0
Net product revenue | Geographic concentration risk
Revenue recognition
Number of countries exceeding 10% of net product sales | country	2	2	1
Percentage of net product sales threshold	10.00%	10.00%	10.00%
Net product revenue | Customer concentration risk
Revenue recognition
Number of distributors | Distributor	2	2	2
Percentage of net product sales threshold	10.00%	10.00%	10.00%
Net product revenue
Revenue recognition
Revenue	$ 661,249	$ 535,228	$ 428,904
Net product revenue | Non-US
Revenue recognition
Revenue	406,100	316,900	241,600
Net product revenue | Net product revenue | Geographic concentration risk | United States
Revenue recognition
Revenue	255,100	218,300
Net product revenue | Net product revenue | Geographic concentration risk | Russia
Revenue recognition
Revenue	86,000	59,700
Emflaza | United States
Revenue recognition
Revenue	255,100	218,300	187,300
Translarna | Non-US
Revenue recognition
Revenue	$ 355,800	$ 288,600	$ 236,000

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