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Fair value of financial instruments and investments - Summary of changes in the fair value of the Company's Level 3 valuation (Details) - Significant unobservable inputs (Level 3) - Agilis - USD ($) $ in Thousands | 3 Months Ended
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Mar. 31, 2024 | Mar. 31, 2023
Upstaza |  |
Changes in the fair value of warrant liability and SARs liability |  |
Ending Balance | $ 36,200 |
Development and Regulatory Milestones | Commitments |  |
Changes in the fair value of warrant liability and SARs liability |  |
Beginning Balance | 26,600 | $ 82,500
Additions | 0 | 0
Change in fair value | 300 | 3,000
Rights Exchange settlement | 0 | 0
Ending Balance | 26,900 | 85,500
Net Sales Milestones and Royalties | Commitments |  |
Changes in the fair value of warrant liability and SARs liability |  |
Beginning Balance | 9,700 | 81,500
Additions | 0 | 0
Change in fair value | (400) | (600)
Rights Exchange settlement | 0 | 0
Ending Balance | $ 9,300 | $ 80,900

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- Definition A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period. + References No definition available. + Details
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- Definition Amount of gain (loss) recognized in income from liability measured at fair value on recurring basis using unobservable input (level 3). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482106/820-10-50-2 + Details
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- Definition Amount of settlements of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482106/820-10-50-2 + Details
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