XML 43 R29.htm IDEA: XBRL DOCUMENT
v3.24.1.u1

Intangible assets and goodwill - (Tables) | 3 Months Ended
--- | ---
Mar. 31, 2024
Goodwill and Intangible Assets Disclosure [Abstract] |
Schedule of definite lived intangible assets | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | Ending Balance at | ​ | ​ | ​ | ​ | ​ | Foreign | ​ | ​ | Ending Balance at | ​ | ​
Definite-lived | ​ | ​ | December 31, | ​ | ​ | ​ | ​ | ​ | currency | ​ | ​ | March 31, | ​ | ​
intangibles assets, gross |  | ​ | 2023 |  | ​ | Additions |  | ​ | translation |  | ​ | 2024 | ​ | ​
Emflaza | ​ | $ | 527,417 | ​ | $ | — | ​ | $ | — | ​ | $ | 527,417 | ​ | ​
Waylivra | ​ | ​ | 10,218 | ​ | ​ | 1,658 | ​ | ​ | (246) | ​ | ​ | 11,630 | ​ | ​
Tegsedi | ​ | ​ | 13,322 | ​ | ​ | 792 | ​ | ​ | (320) | ​ | ​ | 13,794 | ​ | ​
Upstaza | ​ | ​ | 89,550 | ​ | ​ | — | ​ | ​ | — | ​ | ​ | 89,550 | ​ | ​
Total definite-lived intangibles, gross | ​ | $ | 640,507 | ​ | $ | 2,450 | ​ | $ | (566) | ​ | $ | 642,391 | ​ | ​
​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | Ending Balance at | ​ | ​ | ​ | ​ | ​ | Foreign | ​ | ​ | Ending Balance at
Definite-lived | ​ | ​ | December 31, | ​ | ​ | ​ | ​ | ​ | currency | ​ | ​ | March 31,
intangibles assets, accumulated amortization |  | ​ | 2023 |  | ​ | Amortization |  | ​ | translation |  | ​ | 2024
Emflaza | ​ | $ | (478,618) | ​ | $ | (48,799) | ​ | $ | — | ​ | $ | (527,417)
Waylivra | ​ | ​ | (3,965) | ​ | ​ | (366) | ​ | ​ | 106 | ​ | ​ | (4,225)
Tegsedi | ​ | ​ | (3,311) | ​ | ​ | (499) | ​ | ​ | 83 | ​ | ​ | (3,727)
Upstaza | ​ | ​ | (10,882) | ​ | ​ | (1,866) | ​ | ​ | — | ​ | ​ | (12,748)
Total definite-lived intangibles, accumulated amortization | ​ | $ | (496,776) | ​ | $ | (51,530) | ​ | $ | 189 | ​ | $ | (548,117)
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Total definite-lived intangibles, net | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | $ | 94,274
​
Schedule of estimated future amortization of intangible assets | ​
​ | ​ | ​ | ​
​ |  | As of March 31, 2024
2024 | ​ | $ | 8,182
2025 | ​ |  | 10,898
2026 | ​ |  | 10,898
2027 | ​ |  | 10,898
2028 and thereafter | ​ |  | 53,398
Total | ​ | $ | 94,274
Schedule of indefinite lived intangible assets | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | Ending Balance at | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | Ending Balance at | ​
Indefinite-lived | ​ | ​ | December 31, | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | March 31, | ​
intangibles assets |  | ​ | 2023 |  | ​ | Additions |  | ​ | Impairment |  | ​ | 2024 |
Upstaza | ​ | $ | 235,766 | ​ | $ | — | ​ | $ | — | ​ | $ | 235,766 | ​
Total indefinite-lived intangibles | ​ | $ | 235,766 | ​ | $ | — | ​ | $ | — | ​ | $ | 235,766 | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Total intangible assets, net | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | $ | 330,040 | ​
​

X
- References No definition available. + Details
Name: | us-gaap_GoodwillAndIntangibleAssetsDisclosureAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of assets, excluding financial assets and goodwill, lacking physical substance with a finite life, by either major class or business segment. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482665/350-30-50-1 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 2 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482665/350-30-50-2 + Details
Name: | us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of assets, excluding financial assets and goodwill, lacking physical substance and exist in perpetuity, by either major class or business segment. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 350 -SubTopic 30 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482665/350-30-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Subparagraph (b),(d) -SubTopic 30 -Topic 350 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482665/350-30-50-3 + Details
Name: | us-gaap_ScheduleOfIndefiniteLivedIntangibleAssetsTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- Definition Tabular disclosure of the amount of amortization expense expected to be recorded in succeeding fiscal years for finite-lived intangible assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 2 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482665/350-30-50-2 + Details
Name: | us-gaap_ScheduleofFiniteLivedIntangibleAssetsFutureAmortizationExpenseTableTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration