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Intangible assets and goodwill - (Tables)
3 Months Ended
Mar. 31, 2024
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of definite lived intangible assets

Ending Balance at

Foreign

Ending Balance at

Definite-lived

December 31,

currency

March 31,

intangibles assets, gross

    

2023

    

Additions

    

translation

    

2024

Emflaza

$

527,417

$

$

$

527,417

Waylivra

10,218

1,658

(246)

11,630

Tegsedi

13,322

792

(320)

13,794

Upstaza

89,550

89,550

Total definite-lived intangibles, gross

$

640,507

$

2,450

$

(566)

$

642,391

Ending Balance at

Foreign

Ending Balance at

Definite-lived

December 31,

currency

March 31,

intangibles assets, accumulated amortization

    

2023

    

Amortization

    

translation

    

2024

Emflaza

$

(478,618)

$

(48,799)

$

$

(527,417)

Waylivra

(3,965)

(366)

106

(4,225)

Tegsedi

(3,311)

(499)

83

(3,727)

Upstaza

(10,882)

(1,866)

(12,748)

Total definite-lived intangibles, accumulated amortization

$

(496,776)

$

(51,530)

$

189

$

(548,117)

Total definite-lived intangibles, net

$

94,274

Schedule of estimated future amortization of intangible assets

    

As of March 31, 2024

2024

$

8,182

2025

 

10,898

2026

 

10,898

2027

 

10,898

2028 and thereafter

 

53,398

Total

$

94,274

Schedule of indefinite lived intangible assets

Ending Balance at

Ending Balance at

Indefinite-lived

December 31,

March 31,

intangibles assets

    

2023

    

Additions

    

Impairment

    

2024

    

Upstaza

$

235,766

$

$

$

235,766

Total indefinite-lived intangibles

$

235,766

$

$

$

235,766

Total intangible assets, net

$

330,040