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Summary of significant accounting policies - Collaboration and Royalty Revenue (Details) - USD ($)	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Collaboration and royalty revenue
Revenue	$ 210,118,000	$ 220,382,000
Collaboration revenue
Collaboration and royalty revenue
Revenue		6,000
Royalty revenue
Collaboration and royalty revenue
Revenue	31,154,000	30,831,000
SMA License Agreement | Collaboration revenue
Collaboration and royalty revenue
Revenue	0	0
SMA License Agreement | Royalty revenue
Collaboration and royalty revenue
Revenue	$ 31,200,000	$ 30,800,000

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