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Fair value of financial instruments and investments - Summary of changes in the fair value of the Company's Level 3 valuation (Details) - Significant unobservable inputs (Level 3) - Agilis - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Upstaza    
Changes in the fair value of warrant liability and SARs liability    
Ending Balance $ 36,200  
Development and Regulatory Milestones | Commitments    
Changes in the fair value of warrant liability and SARs liability    
Beginning Balance 26,600 $ 82,500
Additions 0 0
Change in fair value 300 3,000
Rights Exchange settlement 0 0
Ending Balance 26,900 85,500
Net Sales Milestones and Royalties | Commitments    
Changes in the fair value of warrant liability and SARs liability    
Beginning Balance 9,700 81,500
Additions 0 0
Change in fair value (400) (600)
Rights Exchange settlement 0 0
Ending Balance $ 9,300 $ 80,900