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Stock award plan - Share-based compensation expense (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Stock option plan
Share-based compensation expense	$ 18,378	$ 28,815
Unrecognized compensation cost	$ 156,300
Weighted average remaining service period for recognition of unrecognized compensation cost	2 years 4 months 24 days
Research and development
Stock option plan
Share-based compensation expense	$ 8,967	15,314
Selling, general and administrative
Stock option plan
Share-based compensation expense	$ 9,411	$ 13,501

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- Definition

Amount of expense for award under share-based payment arrangement. Excludes amount capitalized.

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Amount of cost not yet recognized for nonvested award under share-based payment arrangement.

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