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Revenue recognition - Collaboration and Royalty Revenue (Details)	3 Months Ended
	Mar. 31, 2024 USD ($) product	Mar. 31, 2023 USD ($)	Nov. 30, 2011 USD ($)
Revenue recognition
Number of approved products | product	2
Remaining potential milestones that can be achieved	$ 150,000,000.0
Revenue	210,118,000	$ 220,382,000
Collaboration revenue
Revenue recognition
Revenue		6,000
Royalty revenue
Revenue recognition
Revenue	$ 31,154,000	30,831,000
SMA License Agreement
Revenue recognition
Number of approved products | product	1
SMA License Agreement | Collaboration revenue
Revenue recognition
Revenue	$ 0	0
SMA License Agreement | Royalty revenue
Revenue recognition
Revenue	31,200,000	$ 30,800,000
Research And Development Event Milestones | SMA License Agreement
Revenue recognition
Remaining potential milestones that can be achieved	0
Sales Milestones | SMA License Agreement
Revenue recognition
Remaining potential milestones that can be achieved	$ 150,000,000.0
Maximum | Research And Development Event Milestones | SMA License Agreement
Revenue recognition
Remaining potential milestones that can be achieved			$ 135,000,000.0
Maximum | Sales Milestones | SMA License Agreement
Revenue recognition
Remaining potential milestones that can be achieved			$ 325,000,000.0

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