
Name (Title)	Action Taken (Date of Action)	Type of Trading Arrangement	Nature of Trading Arrangement	Duration of Trading Arrangement	Aggregate Number of Securities
Matthew Klein (Chief Executive Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2028	Indeterminable (1)
Pierre Gravier (Chief Financial Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2028	Indeterminable (1)
Pierre Gravier (Chief Financial Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2026	Indeterminable (1)
Neil Almstead (Chief Technical Operations Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2028	Indeterminable (1)
Neil Almstead (Chief Technical Operations Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2026	Indeterminable (1)
Mark Boulding (EVP & Chief Legal Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2028	Indeterminable (1)

Mark Boulding (EVP & Chief Legal Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2026	Indeterminable (1)
Lee Golden (EVP & Chief Medical Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2028	Indeterminable (1)
Lee Golden (EVP & Chief Medical Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2026	Indeterminable (1)
Eric Pauwels (Chief Business Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2028	Indeterminable (1)
Eric Pauwels (Chief Business Officer)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2026	Indeterminable (1)
Christine Utter (SVP, Chief Accounting Officer and Head of People Services)	Adoption (February 15, 2024)	Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024	Sale	Until final settlement of RSUs on or around February 15, 2028	Indeterminable (1)

Christine Utter
(SVP,
Chief Accounting Officer and Head of People Services)

Adoption
(February 15, 2024)

Rule 10b5-1 trading arrangement for sell-to-cover transactions for RSUs granted on February 15, 2024

Sale

Until final settlement of RSUs on or around February 15, 2026

Indeterminable (1)

(1) The number of shares subject to this RSU grant that will be sold to satisfy applicable tax withholding obligations upon vesting is unknown as the number will vary based on the extent to which vesting conditions are satisfied and the market price of the Company’s common stock at the time of settlement. This trading arrangement provides for the automatic sale of shares that would otherwise be issuable on each settlement date of the RSU in an amount sufficient to satisfy the applicable withholding obligation, with the proceeds of the sale delivered to the Company in satisfaction of the applicable withholding obligation.

Rule 10b5-1 Arrangement Terminated

false