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Fair value of financial instruments and investments - Summary of changes in the fair value of the Company's Level 3 valuation (Details) - Significant unobservable inputs (Level 3) - Agilis - USD ($) $ in Thousands | 6 Months Ended
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Jun. 30, 2024 | Jun. 30, 2023
Upstaza |  |
Changes in the fair value of warrant liability and SARs liability |  |
Ending Balance | $ 21,300 |
Development and Regulatory Milestones | Commitments |  |
Changes in the fair value of warrant liability and SARs liability |  |
Beginning Balance | 26,600 | $ 82,500
Additions | 0 | 0
Change in fair value | 3,200 | (56,100)
Reclassification to accounts payable and accrued expenses | (20,000) |
Rights Exchange settlement | 0 | 0
Ending Balance | 9,800 | 26,400
Net Sales Milestones and Royalties | Commitments |  |
Changes in the fair value of warrant liability and SARs liability |  |
Beginning Balance | 9,700 | 81,500
Additions | 0 | 0
Change in fair value | 1,800 | (70,400)
Reclassification to accounts payable and accrued expenses | 0 |
Rights Exchange settlement | 0 | 0
Ending Balance | $ 11,500 | $ 11,100

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- Definition Amount of transfers of financial instrument classified as a liability out of level 3 of the fair value hierarchy. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-3 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(3) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2 + Details
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- Definition Amount of gain (loss) recognized in income from liability measured at fair value on recurring basis using unobservable input (level 3). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-3 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 820 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482106/820-10-50-2 + Details
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