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Summary of significant accounting policies - Liability for Sale of Future Royalties (Details) $ in Thousands | 1 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2024 USD ($) tranche | Jun. 30, 2024 USD ($)
Assigned royalty payments |  |
Cash received from Royalty Pharma |  | $ 241,792
Effective interest rate of the liability component | 9.90% | 9.90%
A&R Royalty Purchase Agreement |  |
Assigned royalty payments |  |
Cash received from Royalty Pharma | $ 241,800 |
Assigned royalty payment, retained percentage | 9.51% | 9.51%
Royalty purchase agreement termination period once there are no further royalty payment obligations | 60 days |
Effective interest rate of the liability component | 9.90% | 9.90%
Aggregate percentage of royalty rights sold |  | 90.49%
Percentage of maximum royalty payable thereafter assigned royalty rights |  | 83.33%
Liability recognized for sale of future royalties. | $ 241,800 | $ 241,800
Adjusted percentage of retained royalty rights after the 2020 Assigned Royalty Cap is met | 16.67% |
A&R Royalty Purchase Agreement | Maximum |  |
Assigned royalty payments |  |
Number of tranches to sell retained royalty | tranche | 3 |
A&R Royalty Purchase Agreement | Royalty Pharma |  |
Assigned royalty payments |  |
Assigned Royalty Cap per terms of the royalty purchase agreement | $ 1,300,000 | 1,300,000
Aggregate upfront cash consideration received for sale of future royalties |  | 1,900,000
A&R Royalty Purchase Agreement Tranche One |  |
Assigned royalty payments |  |
Aggregate percentage of royalty rights sold | 3.81% |
Contract price for sale of specified percentage of future royalties | $ 100,000 | 100,000
Adjusted percentage of retained royalty rights sold after the 2020 Assigned Royalty Cap is met | 6.67% |
A&R Royalty Purchase Agreement Tranche Two |  |
Assigned royalty payments |  |
Aggregate percentage of royalty rights sold | 3.81% |
Contract price for sale of specified percentage of future royalties | $ 100,000 | 100,000
Adjusted percentage of retained royalty rights sold after the 2020 Assigned Royalty Cap is met | 6.67% |
A&R Royalty Purchase Agreement Tranche Three |  |
Assigned royalty payments |  |
Aggregate percentage of royalty rights sold | 1.90% |
Contract price for sale of specified percentage of future royalties | $ 50,000 | $ 50,000
Adjusted percentage of retained royalty rights sold after the 2020 Assigned Royalty Cap is met | 3.33% |

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