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Stock award plan - (Tables)

6 Months Ended

Jun. 30, 2024

Share-based Payment Arrangement [Abstract]

Summary of stock option activity

​

​	​	​	​	​	​	​	​	​	​	​	​
​		​		​	​		Weighted-			​	​
​	​	​	​	Weighted-		​	average	​	​	Aggregate
​	​	​	​	average		​	remaining	​	​	intrinsic
​	​	Number of	​	exercise		​	contractual	​	​	value(in
​	​	options	​	price		​	term	​	​	thousands)
​	​	​	​	​	​	​	​		​	​	​
Outstanding at December 31, 2023		9,600,399	​	$	43.59				​	​
Granted		864,855	​	$	25.70				​	​
Exercised		(192,210)	​	$	22.10				​	​
Forfeited/Cancelled		(991,305)	​	$	45.80				​	​
Outstanding at June 30, 2024		9,281,739	​	$	42.13		5.77	years	​	$	14,161
Vested or Expected to vest at June 30, 2024		1,904,403	​	$	37.27		8.54	years	​	$	4,115
Exercisable at June 30, 2024		7,177,321	​	$	43.68		4.94	years	​	$	9,453

​

Schedule of assumptions used to estimate fair values of grants made on the date of grant

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​	​	​	​
​		Six months ended
​		June 30, 2024
Risk-free interest rate		4.23% - 4.66%
Expected volatility		53% - 54%
Expected term		5.5 years

Summary of information on the Company's restricted stock

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​	​	​	​	​	​
​	​	Restricted Stock Awards and Units
​	​	​	​	Weighted
​	​	​	​	Average
​	​	​	​	Grant
​	​	Number of	​	Date
​		Shares		Fair Value
Unvested at December 31, 2023	​	2,866,270	​	$	41.82
Granted		1,800,930	​	​	25.72
Vested		(891,879)	​	​	44.35
Forfeited		(172,476)	​	​	37.61
Unvested at June 30, 2024		3,602,845	​	$	33.35

Schedule of share-based compensation expense recorded in the statement of operations

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Three Months Ended June 30,

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Six Months Ended June 30,

​

​

2024

2023

2024

2023

​

Research and development

​

$

9,428

​

$

15,529

​

$

18,395

​

$

30,842

​

Selling, general and administrative

​

9,815

​

13,842

​

19,226

​

27,344

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Total

​

$

19,243

​

$

29,371

​

$

37,621

​

$

58,186

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Tabular disclosure of the changes in outstanding nonvested restricted stock shares.

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-Name Accounting Standards Codification
-Section 50
-Subparagraph (c)
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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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