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Summary of significant accounting policies - Collaboration and Royalty Revenue (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Collaboration and royalty revenue
Revenue	$ 186,704	$ 213,808	$ 396,822	$ 434,190
Collaboration revenue
Collaboration and royalty revenue
Revenue				6
Royalty revenue
Collaboration and royalty revenue
Revenue	53,183	36,853	84,337	67,684
SMA License Agreement | Royalty revenue
Collaboration and royalty revenue
Revenue	$ 53,200	$ 36,900	$ 84,300	$ 67,700

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