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Consolidated Statements of Operations - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Revenues:        
Revenue $ 186,704 $ 213,808 $ 396,822 $ 434,190
Operating expenses:        
Cost of product sales, excluding amortization of acquired intangible assets 15,527 12,731 30,267 26,875
Amortization of acquired intangible assets 2,865 47,397 54,395 86,812
Research and development 132,169 185,874 248,298 380,998
Selling, general and administrative 69,500 88,449 142,772 175,363
Change in the fair value of contingent consideration 5,100 (128,900) 5,000 (126,500)
Intangible asset impairment   217,800   217,800
Tangible asset impairment and losses (gains) on transactions, net 1,761   1,761  
Total operating expenses 226,922 423,351 482,493 761,348
Loss from operations (40,218) (209,543) (85,671) (327,158)
Interest expense, net (43,490) (29,415) (84,324) (56,745)
Other (expense) income, net (2,025) 1,479 (434) 11,434
Loss before income tax (expense) benefit (85,733) (237,479) (170,429) (372,469)
Income tax (expense) benefit (13,446) 38,596 (20,326) 34,627
Net loss attributable to common stockholders $ (99,179) $ (198,883) $ (190,755) $ (337,842)
Weighted-average shares outstanding:        
Basic 76,725,070 74,730,433 76,610,598 74,232,624
Diluted 76,725,070 74,730,433 76,610,598 74,232,624
Net loss per share-basic and diluted (in dollars per share)        
Basic $ (1.29) $ (2.66) $ (2.49) $ (4.55)
Diluted $ (1.29) $ (2.66) $ (2.49) $ (4.55)
Net product revenue        
Revenues:        
Revenue $ 133,220 $ 174,592 $ 310,824 $ 362,149
Collaboration revenue        
Revenues:        
Revenue       6
Royalty revenue        
Revenues:        
Revenue 53,183 36,853 84,337 67,684
Manufacturing revenue        
Revenues:        
Revenue $ 301 $ 2,363 $ 1,661 $ 4,351