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Consolidated Statements of Stockholders' Deficit - USD ($)
$ in Thousands
Common stock
Additional paid-in capital
Accumulated other comprehensive (loss) income
Accumulated deficit
Total
Balance (in shares) at Dec. 31, 2022 73,104,692        
Balance at the beginning of the period at Dec. 31, 2022 $ 72 $ 2,305,020 $ 4,796 $ (2,656,974) $ (347,086)
Balance (in shares) at Mar. 31, 2023 74,012,034        
Balance at the end of the period at Mar. 31, 2023 $ 73 2,339,886 (1,587) (2,795,933) (457,561)
Balance (in shares) at Dec. 31, 2022 73,104,692        
Balance at the beginning of the period at Dec. 31, 2022 $ 72 2,305,020 4,796 (2,656,974) (347,086)
Increase (Decrease) in Stockholders' Equity          
Exercise of options (in shares) 692,612        
Exercise of options $ 1 20,324     20,325
Restricted stock vesting and issuance (in shares) 746,163        
Restricted stock vesting and issuance, net $ 1       1
Issuance of common stock in connection with an employee stock purchase plan (in shares) 117,304        
Issuance of common stock in connection with an employee stock purchase plan   3,805     3,805
Issuance of common stock in connection with a milestone payable (in shares) 657,462        
Issuance of common stock in connection with a milestone payable $ 1 29,569     29,570
Share-based compensation expense   58,186     58,186
Net Income (Loss)       (337,842) (337,842)
Comprehensive (loss) income     (6,227)   (6,227)
Balance (in shares) at Jun. 30, 2023 75,318,233        
Balance at the end of the period at Jun. 30, 2023 $ 75 2,416,904 (1,431) (2,994,816) (579,268)
Balance (in shares) at Mar. 31, 2023 74,012,034        
Balance at the beginning of the period at Mar. 31, 2023 $ 73 2,339,886 (1,587) (2,795,933) (457,561)
Increase (Decrease) in Stockholders' Equity          
Exercise of options (in shares) 481,051        
Exercise of options $ 1 14,273     14,274
Restricted stock vesting and issuance (in shares) 50,382        
Issuance of common stock in connection with an employee stock purchase plan (in shares) 117,304        
Issuance of common stock in connection with an employee stock purchase plan   3,805     3,805
Issuance of common stock in connection with a milestone payable (in shares) 657,462        
Issuance of common stock in connection with a milestone payable $ 1 29,569     29,570
Share-based compensation expense   29,371     29,371
Net Income (Loss)       (198,883) (198,883)
Comprehensive (loss) income     156   156
Balance (in shares) at Jun. 30, 2023 75,318,233        
Balance at the end of the period at Jun. 30, 2023 $ 75 2,416,904 (1,431) (2,994,816) (579,268)
Balance (in shares) at Dec. 31, 2023 75,708,889        
Balance at the beginning of the period at Dec. 31, 2023 $ 75 2,466,233 (1,285) (3,283,578) (818,555)
Increase (Decrease) in Stockholders' Equity          
Exercise of options (in shares) 181,444        
Exercise of options   4,747     4,747
Restricted stock vesting and issuance (in shares) 902,645        
Restricted stock vesting and issuance, net $ 1       1
Issuance of common stock in connection with an employee stock purchase plan (in shares) 107,145        
Issuance of common stock in connection with an employee stock purchase plan   1,973     1,973
Share-based compensation expense   37,621     37,621
Net Income (Loss)       (190,755) (190,755)
Comprehensive (loss) income     (15,213)   (15,213)
Balance (in shares) at Jun. 30, 2024 76,900,123        
Balance at the end of the period at Jun. 30, 2024 $ 76 2,510,574 (16,498) (3,474,333) (980,181)
Balance (in shares) at Mar. 31, 2024 76,653,960        
Balance at the beginning of the period at Mar. 31, 2024 $ 76 2,486,722 (5,560) (3,375,154) (893,916)
Increase (Decrease) in Stockholders' Equity          
Exercise of options (in shares) 71,552        
Exercise of options   2,636     2,636
Restricted stock vesting and issuance (in shares) 67,466        
Issuance of common stock in connection with an employee stock purchase plan (in shares) 107,145        
Issuance of common stock in connection with an employee stock purchase plan   1,973     1,973
Share-based compensation expense   19,243     19,243
Net Income (Loss)       (99,179) (99,179)
Comprehensive (loss) income     (10,938)   (10,938)
Balance (in shares) at Jun. 30, 2024 76,900,123        
Balance at the end of the period at Jun. 30, 2024 $ 76 $ 2,510,574 $ (16,498) $ (3,474,333) $ (980,181)