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Revenue recognition - Net Product Sales (Details)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2024
USD ($)
country
segment
Distributor
Jun. 30, 2023
USD ($)
Distributor
country
segment
Jun. 30, 2024
USD ($)
segment
country
Distributor
Jun. 30, 2023
USD ($)
Distributor
segment
country
Dec. 31, 2023
USD ($)
Revenue recognition          
Number of operating segments | segment 1 1 1 1  
Revenue $ 186,704 $ 213,808 $ 396,822 $ 434,190  
Net product revenue | Geographic concentration risk          
Revenue recognition          
Number of countries exceeding 10% of net product sales | country 2 3 3 3  
Percentage of net product sales threshold 10.00% 10.00% 10.00% 10.00%  
Net product revenue | Geographic concentration risk | United States          
Revenue recognition          
Revenue $ 47,300 $ 65,700 $ 104,800 $ 120,300  
Net product revenue | Geographic concentration risk | Non-US          
Revenue recognition          
Revenue 85,900 108,900 206,000 241,800  
Net product revenue | Geographic concentration risk | Russia          
Revenue recognition          
Revenue   19,100 54,800 63,700  
Net product revenue | Geographic concentration risk | Brazil          
Revenue recognition          
Revenue $ 30,400 $ 23,100 $ 39,100 $ 48,900  
Net product revenue | Customer concentration risk          
Revenue recognition          
Number of distributors | Distributor 2 2 2 2  
Percentage of net product sales threshold 10.00% 10.00% 10.00% 10.00%  
Product          
Revenue recognition          
Revenue $ 133,220 $ 174,592 $ 310,824 $ 362,149  
Contract with customer, liability 0   0   $ 0
Emflaza | Net product revenue | Geographic concentration risk | United States          
Revenue recognition          
Revenue 47,300 65,700 104,800 120,300  
Translarna | Net product revenue | Geographic concentration risk | Non-US          
Revenue recognition          
Revenue $ 70,400 $ 96,500 $ 173,900 $ 211,600